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Nervenarzt ; 76(4): 475-8, 2005 Apr.
Article in German | MEDLINE | ID: mdl-15221068

ABSTRACT

The case of inflammatory vasculopathy and encephalopathy caused by treatment with tacrolimus is reported. This 49-year-old woman developed progressive gait ataxia and right-sided hemiparesis after 7 years of tacrolimus therapy for focal sclerosing glomerulonephritis. MRI presented multifocal cerebral lesions with contrast enhancement. Oligoclonal banding was positive. When the treatment with tacrolimus was stopped, the clinical symptoms resolved completely and the MRI findings improved with corticoid monotherapy.


Subject(s)
Encephalitis/chemically induced , Encephalitis/prevention & control , Tacrolimus/adverse effects , Tacrolimus/therapeutic use , Vasculitis, Central Nervous System/chemically induced , Vasculitis, Central Nervous System/prevention & control , Female , Humans , Immunosuppressive Agents/adverse effects , Immunosuppressive Agents/therapeutic use , Middle Aged , Vasculitis, Central Nervous System/diagnosis
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