Is there an association between early childhood caries and iron deficiency anaemia?

Clinical question To determine the association between early childhood caries (ECC) and iron deficiency anaemia (IDA).Data sources A systematic search was carried out in seven databases by two independent reviewers. Also, manual searching and grey literature screening were carried out.Study selection Cross-sectional, case-control and cohort studies that evaluated the association between ECC and IDA were included. Only publications in the English language were considered for study eligibility.Data extraction and synthesis The characteristics of the included studies - age, sex, sample size, diagnostic methods used, index used for ECC, blood parameters, odds ration/risk ratio, confidence interval, p value, outcomes and assessment of any confounders - were extracted from the included papers. The quality assessment for case-control and cohort studies was performed according to the Newcastle-Ottawa assessment scale, while the modified Newcastle-Ottawa assessment scale was used for the cross-sectional studies.Results A total of 14 publications were included for qualitative review and seven of them were included in the meta-analysis. Children affected by ECC had an increased likelihood of IDA when compared to those not affected by ECC. However, the meta-analysis showed no statistical difference in blood parameters (haemoglobin, mean corpuscular volume and serum ferritin) in children with and without ECC.Conclusions There is an association between ECC and increased odds of IDA; however, there is a lack of scientific evidence to determine a cause and effect relation or direction of association between ECC and IDA.

General and paediatric dentists' knowledge, attitude and practises regarding the use of Silver Diammine Fluoride for the management of dental caries: a national survey in the Netherlands.

BACKGROUND: Silver Diammine Fluoride (SDF) is a topical medication used to arrest cavitated carious lesions non-invasively. The primary aim was to investigate, and analyse the relationships between; knowledge, attitudes and practises (including barriers and facilitators) for SDF use in the management of dental caries by general dental practitioners (GDPs) and paediatric dentists (PDs) in the Netherlands. A secondary aim was to explore any differences in these, between these groups. METHODS: A randomly selected sample of 600 Dutch GDPs (out of 9,502 respectively) and all 57 registered Dutch PDs were invited to participate in this cross-sectional survey, consisting of four sections: (1) participant characteristics, (2) knowledge (through responses to summative questions), (3) attitudes (through statement agreement using 5-point Likert scale), and (4) practises, use, barriers and facilitators (through multiple choice questions). RESULTS: The response rates were: GDPs 23% (n = 140) and PDs 47% (n = 27). Knowledge: out of 15 questions to test understanding of SDF, the mean number of correct answers were GDPs 6.7; standard deviation (SD) 2.6 and PDs 7.4, SD 2.2 with no significant difference. The mean overall attitude score showed positive attitudes towards SDF use for both groups. Compared to GDPs, PDs were more likely to use SDF (p < 0.001) and expected to increase their use (p = 0.037). The main barrier for users was parental acceptance (47%) and for non-users it was lack of knowledge (60%). The main facilitator for both users and non-users was gaining knowledge through courses and workshops, followed by written information leaflets about SDF for parents. CONCLUSION: Less than half of the knowledge questions about SDF were answered correctly. Despite low knowledge, attitude towards SDF use was positive. Practitioners believed that its use would be facilitated by professionals having more accessible information and training and by the availability of parent information leaflets. Furthermore, SDF is used more frequently by PDs than GDPs.

Malocclusion complexity and orthodontic treatment need in children with autism spectrum disorder.

OBJECTIVES: This study aimed to investigate the malocclusion complexity and orthodontic treatment need among children with and without autism spectrum disorder (ASD) referred for orthodontic treatment by quantifying the Discrepancy Index (DI) and Index of Orthodontic Treatment Need (IOTN). MATERIALS AND METHODS: Dental records of 48 ASD and 49 non-ASD consecutive patients aged between 9 and 18 years (median age 13.0 years) referred for orthodontic treatment were reviewed and compared. The Discrepancy Index (DI) was quantified to determine the malocclusion complexity, and the Index of Orthodontic Treatment Need (IOTN), including the Dental Health Component (IOTN-DHC) and Aesthetic Component (IOTN-AC), was quantified to determine the orthodontic treatment need. Statistical analysis included descriptive analysis, Pearson chi-square tests, Fisher's exact test, Mann-Whitney U tests, and several univariate and multivariate regression analyses. The statistical analysis used descriptive analysis, Pearson chi-square test, Fisher's exact test, and multivariate logistic regression. RESULTS: The results show that both malocclusion complexity (DI, p = 0.0010) and orthodontic treatment need (IOTN-DHC, p = 0.0025; IOTN-AC p = 0.0009) were significantly higher in children with ASD. Furthermore, children with ASD had a higher prevalence of increased overjet (p = .0016) and overbite (p = .031). CONCLUSIONS: Malocclusion complexity and orthodontic treatment need are statistically significantly higher among children with ASD than children without ASD, independent of age and sex. CLINICAL RELEVANCE: Children with autism may benefit from visits to a dental specialist (orthodontist) to prevent, to some extent, developing malocclusions from an early age.

Glass Ionomer Sealants Can Prevent Dental Caries but Cannot Prevent Posteruptive Breakdown on Molars Affected by Molar Incisor Hypomineralization: One-Year Results of a Randomized Clinical Trial.

To evaluate the preventive effect of glass ionomer cement (GIC) against dental caries and posteruptive breakdown (PEB) on molars affected by molar incisor hypomineralization (MIH). In this randomized clinical trial, 77 children aged 5-9 years with at least 1 MIH-affected molar and without PEB or dentin caries lesions (n = 228) were included and randomly allocated to one of the following groups: (1) MIH-affected molars that remained unsealed and (2) MIH-affected molars that received GIC sealants. Dental caries and PEB were clinically evaluated after 6 and 12 months. Associations between dental caries and PEB with independent variables were evaluated using logistic regression analysis (p < 0.05). The MIH-affected molars allocated to the GIC sealant group were less likely to develop dental caries compared to those allocated to the unsealed group (OR = 0.23; 95% CI 0.06-0.95). Conversely, application of a GIC sealant was not associated with prevention of PEB (p = 0.313). Furthermore, MIH-affected molars presenting yellow-brown opacities were almost 5 times more likely to develop dental caries (p = 0.013) and PEB (p = 0.001) compared to those presenting white-creamy opacities. We can conclude that GIC sealants can prevent dental caries on MIH-affected molars; however, the same protective effect was not observed for PEB.

The efficacy of articaine and lidocaine local anaesthetic in child patients.

Data sourcesCochrane CENTRAL Register of Controlled Trials, Medline, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Embase, SCIEXPANDED (ISI Web of Knowledge).Study selectionTwo reviewers selected randomised clinical trials (RCTs) that compared the efficacy of articaine and lidocaine in pain rating during dental treatment in child patients.Data extraction and synthesisTwo authors extracted data using a standardised form, and risk of bias was assessed based on Cochranes Risk of bias tool for RCTs. Meta-analysis was performed on all included studies (n=6) where self-reported pain during and after dental procedure was recorded, and which compared articaine local anaesthesia (LA) to lidocaine LA in children. Then a sensitive analysis was performed excluding the studies with high overall risk of bias (n=3).ResultsSix studies were included, one had 'low', two had 'moderate/uncertain' and three had 'high' risk of bias. To evaluate the impact of these studies with 'high' overall risk of bias, a sensitivity analysis was performed and even when excluding these studies, children who had articaine reported significantly less pain after procedure. However, during the procedure no difference was found between self-reported pain when articaine infiltration and lidocaine inferior dental nerve block were compared.ConclusionsLow quality evidence suggests no difference in efficacy between lidocaine Inferior alveolar dental nerve blocks and articaine infiltration when used for routine dental treatment in children. Also, no difference was found in self-reported pain between lidocaine and articaine during treatment procedures, but apparently articaine leads to less pain reporting after the procedure. The body of the evidence is quite low due to the substantial heterogeneity in the reported outcomes and the overall high risk of bias of the included studies.

Mechanical behavior of a bi-layer glass ionomer.

OBJECTIVE: A high-viscosity consistency of the glass-ionomer cement (GIC) may lead to poor adaptation into the cavity. The use of a flowable GIC layer seemed to improve its adaptation in approximal restorations in vitro. In this study we assessed the flexural strength of a two-layered GIC, using a flowable GIC as a liner (two-layer technique). Additionally, finite element analysis on standardized bar-shaped models and on a representative tooth model was performed to rationalize the obtained results. METHODS: The flexural strength and Young's modulus were calculated from the results of a three-point-bending test. Bar-shaped specimens were prepared either with a conventional GIC, with a flowable GIC (powder/liquid ratio 1:2), or with two-layers (either with the flowable layer down or on the top of the specimen). Three dimensional FEA models of the bar-shaped specimens and a model of tooth 46 provided information on the stress distribution of each component of the specimen and on the restoration. RESULTS: The apparent flexural strength and Young's modulus of both two-layered groups were significantly lower than that of the conventional group. FEA showed that the layers of the two-layer specimens with the flowable GIC down separated from each other under load. The tooth model showed better stress distribution for the two-layer restorations. SIGNIFICANCE: The two-layer GIC showed inferior flexural strength, which might be explained by the detachment of the layers under load. Nevertheless the tooth model showed that the two-layer GIC provides a lower stress concentration on the occlusal surface of the material.