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5.
J Biol Buccale ; 5(3): 245-59, 1977 Sep.
Article in French | MEDLINE | ID: mdl-122697

ABSTRACT

Calcium plays an important role in phenomena relating to permeability and regulation of the extracellular compartments. The diffusion anomalies of sulphur previously observed in the oral epithelium of the hypocalcemic rat could possibly be attributed to a reduction in diffusion of sulphur related to disturbances in cellular renewal. The injection of H3 thymidine was used to compare in parathyroidectomized and control rats the resultant differences in DNA synthesis and the migration of labelled cells. The labelling indices showed the absence of any relation between DNA synthesis and a calcium deficiency, whereas, on the contrary, hypocalcemia should produce modifications of the labelled cell distribution in the control and experimental rats. This difference indicates a reduction in cellular migration in case of hypocalcemia.


Subject(s)
Hypocalcemia/physiopathology , Mouth Mucosa/pathology , Animals , Calcium/blood , Cell Division/physiology , Cell Movement/physiology , DNA/biosynthesis , Epithelium/pathology , Hypocalcemia/blood , Hypocalcemia/metabolism , Male , Mouth Mucosa/metabolism , Parathyroidectomy , Rats , Rats, Inbred Strains , Thymidine/metabolism
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