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Cancer Chemother Pharmacol ; 23(2): 119-20, 1989.
Article in English | MEDLINE | ID: mdl-2910508

ABSTRACT

The administration of a diarylsulfonylurea, LY186641, which is presently undergoing a multicentric phase I clinical trial as an anticancer agent, produces major analytical interference with commonly used creatinine analysis techniques. We confirm that this interference is caused by a metabolite rather than the parent compound and propose an alternative, interference-free method.


Subject(s)
Antineoplastic Agents/pharmacology , Creatinine/blood , Sulfonylurea Compounds/pharmacology , Humans
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