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1.
J Clin Sleep Med ; 2024 Apr 24.
Article in English | MEDLINE | ID: mdl-38656805

ABSTRACT

STUDY OBJECTIVES: Hypoglossal nerve stimulation (HGNS) has been widely used to treat obstructive sleep apnea in selected patients. Here we evaluate rates of revision and explant related to HGNS implantation and assess types of adverse events contributing to revision and explant. METHODS: Post-market surveillance data for HGNS implanted between January 1, 2018 and March 31, 2022, were collected. Event rates and risk were calculated using the post-market surveillance event counts and sales volume over the same period. Indications were categorized for analysis. Descriptive statistics were reported and freedom from explant or revision curves were grouped by year of implantation. RESULTS: Of the 20,881 HGNS implants assessed, rates of explant and revision within the first year were 0.723% and 1.542%, respectively. The most common indication for explant was infection (0.378%) and for revision was surgical correction (0.680%). Of the 5,820 devices with three-year post-implantation data, the rate of explant was 2.680% and of revision was 3.557%. During this same interval, elective removal (1.478%) was the most common indication, and for revisions, surgical correction (1.134%). CONCLUSIONS: The efficacy of HGNS is comparable in the real world setting to published clinical trial data. Rates of explant and revision are low, supporting a satisfactory safety profile for this technology.

2.
JAMA Otolaryngol Head Neck Surg ; 150(1): 39-48, 2024 Jan 01.
Article in English | MEDLINE | ID: mdl-38032624

ABSTRACT

Importance: Sham-controlled trials are needed to characterize the effect of hypoglossal nerve stimulation (HGNS) therapy on cardiovascular end points in patients with moderate-severe obstructive sleep apnea (OSA). Objective: To determine the effect of therapeutic levels of HGNS, compared to sham levels, on blood pressure, sympathetic activity, and vascular function. Design, Setting, and Participants: This double-blind, sham-controlled, randomized crossover therapy trial was conducted from 2018 to 2022 at 3 separate academic medical centers. Adult patients with OSA who already had an HGNS device implanted and were adherent and clinically optimized to HGNS therapy were included. Participants who had fallen asleep while driving within 1 year prior to HGNS implantation were excluded from the trial. Data analysis was performed from January to September 2022. Interventions: Participants underwent a 4-week period of active HGNS therapy and a 4-week period of sham HGNS therapy in a randomized order. Each 4-week period concluded with collection of 24-hour ambulatory blood pressure monitoring (ABPM), pre-ejection period (PEP), and flow-mediated dilation (FMD) values. Main Outcomes and Measures: The change in mean 24-hour systolic blood pressure was the primary outcome, with other ABPM end points exploratory, and PEP and FMD were cosecondary end points. Results: Participants (n = 60) were older (mean [SD] age, 67.3 [9.9] years), overweight (mean [SD] body mass index, calculated as weight in kilograms divided by height in meters squared, 28.7 [4.6]), predominantly male (38 [63%]), and had severe OSA at baseline (mean [SD] apnea-hypopnea index, 33.1 [14.9] events/h). There were no differences observed between active and sham therapy in 24-hour systolic blood pressure (mean change on active therapy, -0.18 [95% CI, -2.21 to 1.84] mm Hg), PEP (mean change on active therapy, 0.11 [95% CI, -5.43 to 5.66] milliseconds), or FMD (mean change on active therapy, -0.17% [95% CI, -1.88% to 1.54%]). Larger differences between active and sham therapy were observed in a per-protocol analysis set (n = 20) defined as experiencing at least a 50% reduction in apnea-hypopnea index between sham and active treatment. Conclusions and Relevance: In this sham-controlled HGNS randomized clinical trial, mean 24-hour systolic blood pressure and other cardiovascular measures were not significantly different between sham and active HGNS therapy. Several methodologic lessons can be gleaned to inform future HGNS randomized clinical trials. Trial Registration: ClinicalTrials.gov Identifier: NCT03359096.


Subject(s)
Electric Stimulation Therapy , Sleep Apnea, Obstructive , Adult , Aged , Female , Humans , Male , Blood Pressure , Blood Pressure Monitoring, Ambulatory , Electric Stimulation Therapy/methods , Hypoglossal Nerve , Sleep Apnea, Obstructive/complications , Treatment Outcome , Middle Aged
3.
J Clin Sleep Med ; 19(12): 1989-1995, 2023 12 01.
Article in English | MEDLINE | ID: mdl-37485676

ABSTRACT

STUDY OBJECTIVES: We evaluated the quality of ChatGPT responses to questions on obstructive sleep apnea for patient education and assessed how prompting the chatbot influences correctness, estimated grade level, and references of answers. METHODS: ChatGPT was queried 4 times with 24 identical questions. Queries differed by initial prompting: no prompting, patient-friendly prompting, physician-level prompting, and prompting for statistics/references. Answers were scored on a hierarchical scale: incorrect, partially correct, correct, correct with either statistic or referenced citation ("correct+"), or correct with both a statistic and citation ("perfect"). Flesch-Kincaid grade level and citation publication years were recorded for answers. Proportions of responses at incremental score thresholds were compared by prompt type using chi-squared analysis. The relationship between prompt type and grade level was assessed using analysis of variance. RESULTS: Across all prompts (n = 96 questions), 69 answers (71.9%) were at least correct. Proportions of responses that were at least partially correct (P = .387) or correct (P = .453) did not differ by prompt; responses that were at least correct+ (P < .001) or perfect (P < .001) did. Statistics/references prompting provided 74/77 (96.1%) references. Responses from patient-friendly prompting had a lower mean grade level (12.45 ± 2.32) than no prompting (14.15 ± 1.59), physician-level prompting (14.27 ± 2.09), and statistics/references prompting (15.00 ± 2.26) (P < .0001). CONCLUSIONS: ChatGPT overall provides appropriate answers to most questions on obstructive sleep apnea regardless of prompting. While prompting decreases response grade level, all responses remained above accepted recommendations for presenting medical information to patients. Given ChatGPT's rapid implementation, sleep experts may seek to further scrutinize its medical literacy and utility for patients. CITATION: Campbell DJ, Estephan LE, Mastrolonardo EV, Amin DR, Huntley CT, Boon MS. Evaluating ChatGPT responses on obstructive sleep apnea for patient education. J Clin Sleep Med. 2023;19(12):1989-1995.


Subject(s)
Physicians , Sleep Apnea, Obstructive , Humans , Patient Education as Topic , Sleep Apnea, Obstructive/therapy , Sleep , Software
4.
Int Forum Allergy Rhinol ; 13(7): 1061-1482, 2023 07.
Article in English | MEDLINE | ID: mdl-36068685

ABSTRACT

BACKGROUND: Evaluation and interpretation of the literature on obstructive sleep apnea (OSA) allows for consolidation and determination of the key factors important for clinical management of the adult OSA patient. Toward this goal, an international collaborative of multidisciplinary experts in sleep apnea evaluation and treatment have produced the International Consensus statement on Obstructive Sleep Apnea (ICS:OSA). METHODS: Using previously defined methodology, focal topics in OSA were assigned as literature review (LR), evidence-based review (EBR), or evidence-based review with recommendations (EBR-R) formats. Each topic incorporated the available and relevant evidence which was summarized and graded on study quality. Each topic and section underwent iterative review and the ICS:OSA was created and reviewed by all authors for consensus. RESULTS: The ICS:OSA addresses OSA syndrome definitions, pathophysiology, epidemiology, risk factors for disease, screening methods, diagnostic testing types, multiple treatment modalities, and effects of OSA treatment on multiple OSA-associated comorbidities. Specific focus on outcomes with positive airway pressure (PAP) and surgical treatments were evaluated. CONCLUSION: This review of the literature consolidates the available knowledge and identifies the limitations of the current evidence on OSA. This effort aims to create a resource for OSA evidence-based practice and identify future research needs. Knowledge gaps and research opportunities include improving the metrics of OSA disease, determining the optimal OSA screening paradigms, developing strategies for PAP adherence and longitudinal care, enhancing selection of PAP alternatives and surgery, understanding health risk outcomes, and translating evidence into individualized approaches to therapy.


Subject(s)
Sleep Apnea, Obstructive , Adult , Humans , Sleep Apnea, Obstructive/diagnosis , Sleep Apnea, Obstructive/epidemiology , Sleep Apnea, Obstructive/therapy , Continuous Positive Airway Pressure/methods , Polysomnography/methods , Risk Factors
5.
Am J Otolaryngol ; 42(2): 102866, 2021.
Article in English | MEDLINE | ID: mdl-33418179

ABSTRACT

Obstructive sleep apnea (OSA) has become increasingly prevalent in the United States. While continuous positive airway pressure (CPAP) therapy remains the gold standard for treatment, surgical intervention can enhance compliance and improve outcomes for those intolerant of CPAP. Since the majority of OSA patients have multilevel obstruction, it is critical that otolaryngologists understand each patient's pattern and anatomic level of obstruction before solidifying a treatment plan. This publication serves as a comprehensive review of evaluation, characterization, and management of OSA. Further, the authors outline their departmental algorithm for identifying ideal surgical candidates and tailoring corresponding surgical interventions.


Subject(s)
Continuous Positive Airway Pressure/methods , Patient Selection , Sleep Apnea, Obstructive/surgery , Sleep Apnea, Obstructive/therapy , Algorithms , Female , Humans , Male , Otorhinolaryngologic Surgical Procedures , Patient Compliance , Polysomnography , Sleep Apnea, Obstructive/diagnosis , Sleep Apnea, Obstructive/pathology
6.
Laryngoscope ; 131(7): 1676-1682, 2021 07.
Article in English | MEDLINE | ID: mdl-33443811

ABSTRACT

OBJECTIVES/HYPOTHESIS: To determine the association between findings of blinded reviews of preoperative drug-induced sleep endoscopy (DISE) and outcomes of hypoglossal nerve stimulation (HNS) for obstructive sleep apnea (OSA). STUDY DESIGN: Cohort study. METHODS: A retrospective, multicenter cohort study of 343 adults who underwent treatment of OSA with HNS from 10 academic medical centers was performed. Preoperative DISE videos were scored by four blinded reviewers using the VOTE Classification and evaluation of a possible primary structure contributing to airway obstruction. Consensus DISE findings were examined for an association with surgical outcomes based on therapy titration polysomnogram (tPSG). Treatment response was defined by a decrease of ≥50% in the apnea-hypopnea index (AHI) to <15 events/hour. RESULTS: Study participants (76% male, 60.4 ± 11.0 years old) had a body mass index of 29.2 ± 3.6 kg/m2 . AHI decreased (35.6 ± 15.2 to 11.0 ± 14.1 events/hour; P < .001) on the tPSG, with a 72.6% response rate. Complete palate obstruction (vs. none) was associated with the greatest difference in AHI improvement (-26.8 ± 14.9 vs. -19.2 ± 12.8, P = .02). Complete (vs. partial/none) tongue-related obstruction was associated with increased odds of treatment response (78% vs. 68%, P = .043). Complete (vs. partial/none) oropharyngeal lateral wall-related obstruction was associated with lower odds of surgical response (58% vs. 74%, P = .042). CONCLUSIONS: The DISE finding of primary tongue contribution to airway obstruction was associated with better outcomes, whereas the opposite was true for the oropharyngeal lateral walls. This study suggests that the role for DISE in counseling candidates for HNS extends beyond solely for excluding complete concentric collapse related to the velum. LEVEL OF EVIDENCE: 3 Laryngoscope, 131:1676-1682, 2021.


Subject(s)
Airway Obstruction/diagnosis , Electric Stimulation Therapy/methods , Endoscopy/methods , Hypoglossal Nerve , Sleep Apnea, Obstructive/therapy , Aged , Airway Obstruction/etiology , Airway Obstruction/therapy , Contraindications, Procedure , Counseling , Electric Stimulation Therapy/adverse effects , Electric Stimulation Therapy/instrumentation , Female , Humans , Hypnotics and Sedatives/administration & dosage , Implantable Neurostimulators , Male , Middle Aged , Oropharynx/diagnostic imaging , Palate/diagnostic imaging , Polysomnography , Preoperative Period , Retrospective Studies , Severity of Illness Index , Sleep/drug effects , Sleep Apnea, Obstructive/complications , Sleep Apnea, Obstructive/diagnosis , Tongue/diagnostic imaging , Treatment Outcome
7.
J Neurol Surg B Skull Base ; 82(4): 432-436, 2021 Aug.
Article in English | MEDLINE | ID: mdl-35573919

ABSTRACT

Objective Patients undergoing endoscopic endonasal surgery have historically been restricted from using straws postoperatively, due to the concern that this activity generates negative pressure. The objective of this study is to evaluate the pressure dynamics in the sinonasal cavity associated with the use of a straw. Methods Intracranial pressure catheters were placed in the nasal cavity of 20 healthy individuals. Pressure measurements were then recorded while participants drank liquids of different viscosities from a cup and from a straw. Measurements were recorded with and without subjects occluding their nose to simulate postoperative nasal obstruction. Results The average pressure in the nasal cavity while drinking water from a cup was -0.86 cmH 2 O, from a straw was -1.09 cmH 2 O, and while occluding the nose and using a straw was -0.81 cmH 2 O. The average pressure in the nasal cavity while drinking a milkshake from a cup was -0.98 cmH 2 O, from a straw was -1.88 cmH 2 O, and while occluding the nose and using a straw was -1.37 cmH 2 O. There was no statistically significant difference in pressure measurements when comparing either task or consistency ( p > 0.05). Conclusion Straw use is not associated with the generation of significant negative pressure in the nasal cavity. The pressure generated when drinking from a straw is not significantly different from that of drinking from a cup. This data suggest that straw use may be safe for patients following endoscopic skull base surgery, but further investigation is warranted.

8.
Laryngoscope ; 131(3): E1013-E1018, 2021 03.
Article in English | MEDLINE | ID: mdl-32936959

ABSTRACT

OBJECTIVES/HYPOTHESIS: For patients with obstructive sleep apnea (OSA) undergoing sinonasal surgery, there is a lack of consensus on the risk and appropriate postoperative use of continuous positive airway pressure (CPAP). The aim of this study was to assess the tolerability of restarting CPAP on postoperative day one. STUDY DESIGN: Prospective cohort study. METHODS: A prospective study on patients with OSA on CPAP who required a septoplasty/turbinectomy and/or functional endoscopic sinus surgery (FESS) was performed. Data from the memory card of a patient's CPAP machine and subjective information were obtained on the day of surgery and at scheduled follow-up visits. All subjects were instructed to restart CPAP on the first postoperative night. RESULTS: A total of 14 patients were analyzed; nine underwent FESS and five had a septoplasty/turbinectomy. There were no postoperative complications encountered. The only significant change in the first postoperative week was a reduction in the percentage of nights used over 4 hours (P < .05). By the third postoperative visit, average 22-item Sino-Nasal Outcome Test, Nasal Obstruction Symptom Evaluation, and CPAP tolerance scores improved from preoperative values. CPAP pressures, residual apnea-hypopnea index, and number of hours and mean percentage of nights used remained stable throughout the study period. CONCLUSIONS: Both quality-of-life and CPAP outcomes improved or remained the same when restarting CPAP immediately postoperatively. Combined with a lack of significant complications, this study suggests that CPAP is well-tolerated when restarted the day after a septoplasty/turbinectomy or FESS. LEVEL OF EVIDENCE: 4 Laryngoscope, 131:E1013-E1018, 2021.


Subject(s)
Continuous Positive Airway Pressure/adverse effects , Nasal Obstruction/surgery , Nasal Surgical Procedures/adverse effects , Paranasal Sinuses/surgery , Sleep Apnea, Obstructive/therapy , Adult , Aged , Continuous Positive Airway Pressure/standards , Female , Follow-Up Studies , Humans , Male , Middle Aged , Nasal Obstruction/complications , Postoperative Period , Prospective Studies , Quality of Life , Sleep Apnea, Obstructive/complications , Time Factors , Time-to-Treatment/standards , Treatment Outcome
9.
Am J Rhinol Allergy ; 34(4): 487-493, 2020 Jul.
Article in English | MEDLINE | ID: mdl-32102551

ABSTRACT

BACKGROUND: For patients with obstructive sleep apnea (OSA), there is a lack of knowledge regarding the impact of continuous positive airway pressure (CPAP) on the nasal cavity. There is a significant need for evidence-based recommendations regarding the appropriate use of CPAP following endoscopic sinus and skull base surgery. OBJECTIVE: The goal of this study is to translate a previously developed cadaveric model for evaluating CPAP pressures in the sinonasal cavity by showing safety in vivo and quantifying the effect of positive pressurized air flow on the nasal cavity of healthy individuals where physiologic effects are at play. METHODS: A previously validated cadaveric model using intracranial sensor catheters has proved to be a reliable technique for measuring sinonasal pressures. These sensors were placed in the nasal cavity of 18 healthy individuals. Pressure within the nose was recorded at increasing levels of CPAP. RESULTS: Overall, nasal cavity pressure was on average 85% of delivered CPAP. The amount of pressure delivered to the nasal cavity increased as the CPAP increased. The percentage of CPAP delivered was 77% for 5 cmH2O and increased to 89% at 20 cmH2O. There was a significant difference in mean intranasal pressures between all the levels of CPAP except 5 cmH2O and 8 cmH2O (P < .001). CONCLUSION: On average, only 85% of the pressure delivered by CPAP is transmitted to the nasal cavity. Higher CPAP pressures delivered a greater percentage of pressurized air to the nasal cavity floor. Our results are comparable to the cadaver model, which demonstrated similar pressure delivery even in the absence of anatomic factors such as lung compliance, nasal secretions, and edema. This study demonstrates the safety of using sensors in the human nasal cavity. This technology can also be utilized to evaluate the resiliency of various repair techniques for endoscopic skull base surgery with CPAP administration.


Subject(s)
Continuous Positive Airway Pressure/methods , Nasal Cavity/physiology , Postoperative Complications/therapy , Skull Base/surgery , Sleep Apnea, Obstructive/prevention & control , Administration, Intranasal , Adult , Cadaver , Endoscopy , Evidence-Based Medicine , Female , Humans , Male , Models, Anatomic , Sleep Apnea, Obstructive/etiology
10.
Laryngoscope ; 129(8): 1949-1953, 2019 08.
Article in English | MEDLINE | ID: mdl-30444012

ABSTRACT

OBJECTIVES/HYPOTHESIS: Upper airway stimulation has demonstrated marked improvements in apnea-hypopnea index, oxygen desaturation index, and quality-of-life measures in patients with moderate to severe obstructive sleep apnea (OSA) who cannot tolerate continuous positive airway pressure. Cardiac arrhythmias are common in patients with OSA and can require electrical cardioversion. We describe the first four reported cases of hypoglossal nerve stimulator (HGNS) dysfunction after electrical cardioversion and illustrate our operative approach to device troubleshooting and repair. STUDY DESIGN: Retrospective case series. METHODS: A retrospective review of 201 HGNS implantations performed at two academic institutions revealed four cases of HGNS device dysfunction after electrical cardioversion requiring surgical revision. Preoperative and postoperative device performance metrics and electrical cardioversion specifications were retrospectively assessed and compiled for this case series. The senior authors (R.J.S., M.S.B.) detail operative planning and approach for HGNS implantable pulse generator (IPG) replacement. RESULTS: At least two patients with HGNS device dysfunction had received cardioversion via anterolateral electrode pad placement. Three patients had received multiple shocks. All four patients experienced a change in device functionality or complete cessation of functionality after electrocardioversion. Operatively, each patient required replacement of the IPG, with subsequent intraoperative interrogation revealing proper device functionality. CONCLUSION: Counseling for patients with HGNS undergoing external electrical cardioversion should include possible device damage and need for operative replacement. Anteroposterior electrode pad placement should be considered for patients with HGNS who require electrocardioversion. Operative replacement of an HGNS system damaged by electrocardioversion begins with IPG replacement and intraoperative device interrogation. LEVEL OF EVIDENCE: 4 Laryngoscope, 129:1949-1953, 2019.


Subject(s)
Arrhythmias, Cardiac/therapy , Electric Countershock/adverse effects , Electric Stimulation Therapy/instrumentation , Equipment Failure , Implantable Neurostimulators , Sleep Apnea, Obstructive/therapy , Aged , Arrhythmias, Cardiac/etiology , Female , Humans , Hypoglossal Nerve , Male , Quality of Life , Retrospective Studies , Sleep Apnea, Obstructive/complications
11.
Laryngoscope ; 125(3): 680-4, 2015 Mar.
Article in English | MEDLINE | ID: mdl-25290079

ABSTRACT

OBJECTIVES/HYPOTHESIS: The ideal animal experimental tracheostomy technique is one that is 1) safe and easy to perform, 2) requires no tracheostomy tube, and 3) requires minimal cleaning or suctioning to maintain patency. The leporine model for airway injury has been well established and offers an inexpensive and practical animal model for experimental evaluation. However, previous research has demonstrated a high mortality rate with survival airway surgery in rabbits. This study demonstrates the feasibility of airway management in the leporine model using a simple maturing suture tracheostomy that avoids a tracheostomy tube. STUDY DESIGN: Tracheostomy was performed in six New Zealand white rabbits in the setting of survival surgery over a 2-week study period. METHODS: A vertical tracheal incision was made from the second to the sixth tracheal ring. The anterior portion of the tracheal rings was removed and the skin surrounding the stoma was sutured down to the tracheal wall. The lateral tracheal wall was then suspended to the soft tissue in the lateral neck. RESULTS: All six rabbits survived the study period with minimal care and maintained stoma patency until sacrifice. Granulation tissue and edema were noted during the first week and largely resolved by the second week. An average of 5-mm-diameter stoma was measured 14 days after surgery without intraluminal stenosis or laryngeal edema. CONCLUSIONS: This method meets the defined criteria for the ideal experimental tracheostomy, demonstrating potential benefit in a laryngotracheal stenosis model and a rabbit model of evoked phonation.


Subject(s)
Phonation , Tracheal Stenosis/surgery , Tracheotomy/methods , Animals , Disease Models, Animal , Follow-Up Studies , Rabbits , Tracheal Stenosis/physiopathology , Treatment Outcome , Wound Healing
12.
Laryngoscope ; 121(12): 2521-5, 2011 Dec.
Article in English | MEDLINE | ID: mdl-21997884

ABSTRACT

OBJECTIVES/HYPOTHESIS: To investigate patient outcomes with large-diameter bougienage in isolated cricopharyngeal dysfunction and understand how esophageal dilatation can be used as an effective diagnostic and therapeutic modality in treating dysphagia. STUDY DESIGN: Retrospective review. METHODS: A retrospective chart review was performed on 46 patients meeting the criteria for cricopharyngeal dysphagia from 2004 to 2008 presenting in the outpatient setting. Patients were treated with 60 French esophageal dilators. Outcomes were analyzed as a function of symptomatology, manometry, duration of benefit, and safety. RESULTS: Over the period reviewed, 59 dilatations were performed on 46 patients with cricopharyngeal dysfunction. Eight patients were dilated more than once. Four patients were lost to follow-up. The average starting Functional Outcome Swallowing Score (FOSS) was 2.07. Of the patients reviewed, 64.29% experienced an improvement in their FOSS with a median duration of 741 days. There were five minor complications and no major complications. CONCLUSIONS: In the largest series of esophageal dilatation for cricopharyngeal dysfunction in the literature, we found large-bore bougienage to have significant utility due to its efficacy, ease of use, and safety when compared to other modalities such as botulinum injection, balloon dilatation, and cricopharyngeal myotomy.


Subject(s)
Cricoid Cartilage/physiopathology , Deglutition Disorders/therapy , Dilatation/instrumentation , Esophagoscopy/methods , Adolescent , Adult , Aged , Aged, 80 and over , Cohort Studies , Confidence Intervals , Deglutition Disorders/diagnosis , Dilatation/methods , Equipment Design , Equipment Safety , Female , Follow-Up Studies , Humans , Kaplan-Meier Estimate , Logistic Models , Male , Middle Aged , Multivariate Analysis , Odds Ratio , Patient Satisfaction , Retrospective Studies , Risk Assessment , Severity of Illness Index , Treatment Outcome , Young Adult
13.
Ear Nose Throat J ; 90(4): E17, 2011 Apr.
Article in English | MEDLINE | ID: mdl-21500155

ABSTRACT

Rupture of the extracranial carotid arteries or their major branches is known as carotid blowout syndrome (CBS). CBS is a well-recognized complication of cancer of the head and neck and subsequent radiation therapy. A few treatment modalities are available, including open ligation and different endovascular techniques, but questions regarding both the immediate and delayed complications of these procedures persist. In this case report, we describe the management of acute CBS in a 54-year-old man who had previously been treated for follicular thyroid carcinoma. The patient was hemorrhaging from a pseudoaneurysm of the left common carotid artery. A self-expanding polytetrafluoroethylene (Teflon) -covered stent was successfully deployed endovascularly, and this resulted in cessation of the bleeding and restoration of flow through the vessel. We examine the covered-stent approach to treating acute CBS, and we discuss other treatment approaches that have been described in the literature.


Subject(s)
Carotid Artery Injuries/therapy , Carotid Artery, Common , Stents , Humans , Male , Middle Aged , Rupture, Spontaneous/therapy
14.
Facial Plast Surg ; 26(6): 504-10, 2010 Dec.
Article in English | MEDLINE | ID: mdl-21086237

ABSTRACT

Parotid trauma can lead to both short and long-term complications such as bleeding, infection, facial nerve injury, sialocele, and salivary fistula, resulting in pain and disfigurement. Facial injuries inferior to a line extended from the tragus to the upper lip should raise concern for parotid injury. These injuries can be stratified into three regions as they relate to the masseter muscle. Injuries posing the greatest risk of damage to Stensen's duct include those anterior to the posterior border of the masseter and necessitate exploration. When the duct is disrupted, emphasis should be placed on primary repair or re-creation of the papilla; however, proximal ductal lacerations can be treated by ligation of the proximal segment. Isolated parenchymal injury can be treated with more conservative means. Sialocele and salivary fistula can frequently be managed nonoperatively with antibiotics, pressure dressings, and serial aspiration. Anticholinergic medications and the injection of botulinum toxin represent additional measures before resorting to surgical therapies such as tympanic neurectomy or parotidectomy.


Subject(s)
Facial Injuries/surgery , Parotid Gland/injuries , Plastic Surgery Procedures/methods , Postoperative Complications/prevention & control , Humans , Parotid Gland/anatomy & histology , Parotid Gland/surgery , Soft Tissue Injuries/surgery , Surgery, Plastic/methods
15.
Laryngoscope ; 118(2): 222-7, 2008 Feb.
Article in English | MEDLINE | ID: mdl-18303393

ABSTRACT

OBJECTIVES: Percutaneous dilational tracheotomy procedures have been used successfully as a bedside alternative to open surgical tracheotomy. At our institution, we have seen patients with tracheal injuries following this procedure. In this paper, we review those cases to demonstrate that tracheal stenosis is a potential long-term complication of percutaneous dilational tracheotomy. STUDY DESIGN: Case series. METHODS: Patients were evaluated with computed tomography and operative endoscopy. Inpatient and outpatient records were reviewed retrospectively. RESULTS: Nine patients were referred to our practice for management of tracheal stenosis after percutaneous dilational tracheotomy between 2003 and 2006. Presence of anterior tracheal ring compression and destruction or lateral wall collapse was noted in each case. Endoscopy revealed stenosis secondary to anterior tracheal wall injury in all cases. In eight of nine cases, operative intervention was needed to correct the stenotic segment. CONCLUSIONS: It has been demonstrated in the literature that with 20 years of experience, the percutaneous dilational tracheotomy procedure is more affordable, faster to perform, and a generally safe procedure when performed under appropriate conditions. Most case series of percutaneous dilational tracheotomy reveal an equal or lower risk of short-term complications than open tracheotomy. This series demonstrates that tracheal stenosis is a potential long-term complication. Longitudinal follow-up of patients undergoing percutaneous dilational tracheotomy is indicated.


Subject(s)
Endoscopy/methods , Postoperative Complications , Tracheal Stenosis/diagnosis , Tracheal Stenosis/etiology , Tracheotomy/instrumentation , Adolescent , Aged , Dilatation/instrumentation , Female , Humans , Male , Middle Aged , Retrospective Studies , Skin
16.
Laryngoscope ; 117(12): 2093-6, 2007 Dec.
Article in English | MEDLINE | ID: mdl-17909449

ABSTRACT

UNLABELLED: Approximately 6 weeks after an uncomplicated tonsillectomy for chronic tonsillitis, a 37-year-old woman presented to our emergency department with complaints of odynophagia and cervical pain persistent since surgery. Computed tomographic and magnetic resonance imaging revealed cervical spinal osteomyelitis with epidural abscess at C2 to 3. The patient underwent treatment with intravenous antibiotics, operative debridement, and cervical spinal stabilization. She recovered with no neurologic deficit. CONCLUSIONS: Significant infectious complications of tonsillectomy are uncommon, and cervical spinal osteomyelitis and epidural abscess are exceptionally rare occurrences. In the presence of prolonged pain and dysphagia, imaging can be considered to evaluate for such sequelae.


Subject(s)
Cervical Vertebrae , Discitis/etiology , Epidural Abscess/etiology , Tonsillectomy/adverse effects , Adult , Anti-Bacterial Agents/therapeutic use , Debridement , Diagnosis, Differential , Discitis/diagnosis , Discitis/therapy , Epidural Abscess/diagnosis , Epidural Abscess/therapy , Female , Follow-Up Studies , Humans , Magnetic Resonance Imaging , Postoperative Complications , Restraint, Physical/methods , Tomography, X-Ray Computed , Tonsillitis/surgery
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