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Future Microbiol ; 11: 857-64, 2016 Jul.
Article in English | MEDLINE | ID: mdl-27357522

ABSTRACT

AIM: The aim was to study acquisition and persistence of carbapenemase-producing Enterobacteriaceae (CPE) among travelers. MATERIALS & METHODS: Stools from 2001 travelers and 215 nontraveling household members, collected before and immediately post-travel as well as 1, 3, 6 and 12 months upon return, were screened for CPE. RESULTS: Five travelers, all visiting Asia outside the Indian subcontinent, acquired CPE. One traveler persistently carried the same OXA-244 CPE up to 6 months post-travel. Three months after travel, her co-traveling spouse also became positive for this OXA-244 CPE strain, suggesting clonal transmission within this household. CONCLUSION: Acquisition of CPE is not restricted to travelers to the Indian subcontinent and/or to travelers seeking healthcare during travel and can persist up to at least 6 months post-travel.


Subject(s)
Bacterial Proteins/biosynthesis , Carrier State/microbiology , Enterobacteriaceae Infections/transmission , Enterobacteriaceae/enzymology , Enterobacteriaceae/physiology , Travel , beta-Lactamases/biosynthesis , Adult , Asia , Enterobacteriaceae/drug effects , Enterobacteriaceae/isolation & purification , Enterobacteriaceae Infections/ethnology , Enterobacteriaceae Infections/microbiology , Family Characteristics , Feces/microbiology , Female , Humans , Imipenem/pharmacology , Klebsiella pneumoniae/drug effects , Klebsiella pneumoniae/enzymology , Klebsiella pneumoniae/isolation & purification , Male , Microbial Sensitivity Tests , Middle Aged , Time Factors , Young Adult
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