ABSTRACT
The current worldwide situation of dengue infection, and particularly in the American continent, is analyzed taking into account the increasing risk for infection during pregnancy which exists in endemic areas; the consequences of an eventual vertical transmission of the virus are practically unknown yet. We studied 59 women who gave birth to their children between 5 and 9 months after the "peak phase" of the type 2 dengue virus epidemic which broke out in Cuba in 1981. Sera of the mothers and newborns were studied through various serologic techniques in order to detect antibodies; in some cases we tried to isolate the virus, without success, from serum samples taken from the newborns; among these, we found 4 cases with positive IgM. These newborns showed neither apparent fetal damage at birth nor further alterations in a follow-up carried out when they reached 5 years of age. The need of carrying out further studies contributing to establish an adequate management of pregnant women infected by dengue virus is discussed.
Subject(s)
Antibodies, Viral/blood , Dengue/immunology , Immunoglobulin M/blood , Pregnancy Complications, Infectious/immunology , Cuba/epidemiology , Dengue/epidemiology , Female , Humans , Infant, Newborn , Male , Pregnancy , Pregnancy Complications, Infectious/epidemiologyABSTRACT
Se determinaron los niveles de cinc en pelo a 23 mujeres en la última semana de cada trimestre de gestación; se les realizó simultámente una encuesta dietética durante 4 días consecutivos. Los valores encontrados no presentaron diferencias significativas entre trimestres. Se relaciona este hecho con los resultados de la encuesta dietética, y los hábitos alimentarios de la población (AU)
