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1.
Emotion ; 24(2): 397-411, 2024 Mar.
Article in English | MEDLINE | ID: mdl-37616109

ABSTRACT

The COVID-19 pandemic presents challenges to psychological well-being, but how can we predict when people suffer or cope during sustained stress? Here, we test the prediction that specific types of momentary emotional experiences are differently linked to psychological well-being during the pandemic. Study 1 used survey data collected from 24,221 participants in 51 countries during the COVID-19 outbreak. We show that, across countries, well-being is linked to individuals' recent emotional experiences, including calm, hope, anxiety, loneliness, and sadness. Consistent results are found in two age, sex, and ethnicity-representative samples in the United Kingdom (n = 971) and the United States (n = 961) with preregistered analyses (Study 2). A prospective 30-day daily diary study conducted in the United Kingdom (n = 110) confirms the key role of these five emotions and demonstrates that emotional experiences precede changes in well-being (Study 3). Our findings highlight differential relationships between specific types of momentary emotional experiences and well-being and point to the cultivation of calm and hope as candidate routes for well-being interventions during periods of sustained stress. (PsycInfo Database Record (c) 2024 APA, all rights reserved).


Subject(s)
COVID-19 , Pandemics , Humans , Psychological Well-Being , Prospective Studies , Emotions
2.
Geroscience ; 42(5): 1195-1198, 2020 10.
Article in English | MEDLINE | ID: mdl-32780291

ABSTRACT

A summary of the Fourteenth International Symposium on the Neurobiology and Neuroendocrinology of Aging that was held July 15-20, 2018 in Bregenz, Austria, is presented. Seventeen of the speakers that presented at the conference submitted papers relevant to the topic of their presentation as well as overviews of their respective fields and are included in this special issue. The abstracts from each poster presentation as well as the speaker abstracts are also included at the end of the preface to the special issue.


Subject(s)
Aging , Congresses as Topic , Neurobiology , Neuroendocrinology , Austria , Humans
3.
Ann N Y Acad Sci ; 1418(1): 118-136, 2018 04.
Article in English | MEDLINE | ID: mdl-29722030

ABSTRACT

Extension of mammalian health and life span has been achieved using various dietary interventions. We previously reported that restricting dietary methionine (MET) content extends life span only when growth hormone signaling is intact (no life span increase in GH deficiency or GH resistance). To understand the metabolic responses of altered dietary MET in the context of accelerated aging (high GH), the current study evaluated MET and related pathways in short-living GH transgenic (GH Tg) and wild-type mice following 8 weeks of restricted (0.16%), low (0.43%), or enriched (1.3%) MET consumption. Liver MET metabolic enzymes were suppressed in GH Tg compared to diet-matched wild-type mice. MET metabolite levels were differentially affected by GH status and diet. SAM:SAH ratios were markedly higher in GH Tg mice. Glutathione levels were lower in both genotypes consuming 0.16% MET but reduced in GH Tg mice when compared to wild type. Tissue thioredoxin and glutaredoxin were impacted by diet and GH status. The responsiveness to the different MET diets is reflected across many metabolic pathways indicating the importance of GH signaling in the ability to discriminate dietary amino acid levels and alter metabolism and life span.


Subject(s)
Adaptation, Physiological , Growth Hormone/genetics , Methionine/administration & dosage , Animals , Diet , Glutathione/metabolism , Liver/enzymology , Liver/metabolism , Longevity , Male , Methionine/metabolism , Mice , Mice, Transgenic
4.
Exp Gerontol ; 94: 1-3, 2017 08.
Article in English | MEDLINE | ID: mdl-28216411

ABSTRACT

A summary of the Thirteenth International Symposium on the Neurobiology and Neuroendocrinology of Aging that was held July 17-22, 2016 in Bregenz, Austria, is presented. Nineteen of the speakers that presented at the conference submitted review papers covering the topic of their presentation as well as an overview of their respective fields and are included in this special issue. The abstracts from each poster presentation as well as twenty-two of the speaker abstracts are also included at the end of the preface to the special issue.


Subject(s)
Aging , Biomedical Research , Endocrinology , Neurobiology , Age Factors , Aging/genetics , Aging/metabolism , Aging/pathology , Animals , Humans
5.
Exp Gerontol ; 68: 1-2, 2015 Aug.
Article in English | MEDLINE | ID: mdl-25601418

ABSTRACT

A summary of the Twelfth International Symposium on the Neurobiology and Neuroendocrinology of Aging that was held July 27-August 1, 2014 in Bregenz, Austria, is presented. Fifteen of the speakers that presented at the conference submitted review papers covering the topic of their presentation as well as an overview of their respective fields and are included in this special issue. The abstracts from each poster presentation as well as seven of the speakers' abstracts are also included at the end of the preface to the special issue.


Subject(s)
Aging/physiology , Congresses as Topic , Neurobiology , Neuroendocrinology , Austria , Humans
6.
Exp Gerontol ; 48(7): 593-5, 2013 Jul.
Article in English | MEDLINE | ID: mdl-23384820

ABSTRACT

A summary of the Eleventh International Symposium on the Neurobiology and Neuroendocrinology of Aging that was held in July 29-August 3 in Bregenz, Austria, is presented. Sixteen of the speakers who presented at the conference submitted review papers covering the topic of their presentation as well as an overview of their respective fields and are included in this special issue. The abstracts from each poster presentation are also included at the end of the special issue.


Subject(s)
Aging/physiology , Biomedical Research , Neurobiology , Neuroendocrinology , Age Factors , Animals , Humans
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