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1.
Biochim Biophys Acta Biomembr ; 1866(7): 184352, 2024 Jun 20.
Article in English | MEDLINE | ID: mdl-38908499

ABSTRACT

This work is devoted to the study of the combined effects of applied magnetic field and MNPs on the electrical characteristics of bilayer lipid membranes. We present results of the study of electrical parameters of azolectin membranes in a static inhomogeneous magnetic field at the one-sided addition of positively charged quasi-spherical superparamagnetic magnetite nanoparticles with a diameter of about 4 nm. The magnet was located at different distances from the membrane, and the magnetic field attracted the nanoparticles to the membrane surface with different strengths. We observed three pronounced effects that depended on the external magnetic field. Firstly, after addition of nanoparticles in a magnetic field, the conductance of the membranes increased. A smooth increase in conductance was accompanied in some cases by the appearance of current jumps, which can be associated with the formation of through pores with a radius of no more than 1 nm. The conductance increased with increasing magnetic field gradient. Secondly, at zero command voltage, a negative current through the membrane was observed. Although our experiments did not allow us to unambiguously determine which particles create this current, we believe that this current is associated with the penetration of particles through the membrane. This effect intensified with increasing magnetic field gradient. Thirdly, we observed a sharp change in the nonlinear dependence of capacitance on voltage associated both with the change in the surface potential of the azolectin membrane and with the effect of MNP binding to the membrane surface on the apparent membrane capacitance.

2.
Anesteziol Reanimatol ; (2): 30-5, 1998.
Article in Russian | MEDLINE | ID: mdl-9612967

ABSTRACT

The causes of lethal outcomes (n = 60) and postoperative complications which occurred in 26.1% of 610 patients operated on for lung cancer were investigated with due consideration for the regularities of thermodynamics of nonequilibrium processes and theory of disasters. A total systems pathological inflammatory reaction, which augments the injury by many times and develops as a result of inadequate anesthesiological protection, underlies the development of the most unfavorable variant of response to surgery leading to life-threatening complications, such as pneumonia, thromboembolism, or ulcerative hemorrhages.


Subject(s)
Lung Neoplasms/surgery , Postoperative Complications/etiology , Blood Loss, Surgical , Humans , Lung Neoplasms/mortality , Middle Aged , Pneumonectomy , Postoperative Complications/mortality , Preoperative Care , Respiration, Artificial , Risk Factors
8.
Fiziol Zh SSSR Im I M Sechenova ; 63(8): 1083-7, 1977 Aug.
Article in Russian | MEDLINE | ID: mdl-913660

ABSTRACT

The echo-location characteristics were studied in dolphins with the aid of transformation of stimuli not altering the reception characteristics in analysing systems. The dolphin locator was shown to be able to single out a class of equivalent in respect to certain transformations echo-signals. The probability of the target recognition is invariable in respect to transformations of homothetic type and module transformations, i.e. the principle of invariability spreads over the work of dolphin's auditory analyser in active regimen too.


Subject(s)
Dolphins/physiology , Echolocation/physiology , Neural Analyzers/physiology , Orientation/physiology , Animals
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