ABSTRACT
Studies with infected animals showed that riboxine (inosine) having anabolic, antifibrotic, immunostimulating, antihypoxic and hepatoprotective activities, by the level of its therapeutic effect was not inferior to levamisole or sodium oxybutyrate and exceeded methyluracil. The evidence of the riboxine therapeutic effect mostly correlated with the antihypoxic activity. The use of riboxine at the early stages in the treatment of new cases with infiltrative destructive tuberculosis of the lungs of lobar and polysegmental extent promoted normalization of gaseous metabolism, significant improvement of capillary blood flow in the destructive zone, earlier and more frequent arresting of intoxication signs, sputum abacillation and elimination of the destructive cavities.
