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1.
Adv Exp Med Biol ; 1020: 17-24, 2017.
Article in English | MEDLINE | ID: mdl-28236123

ABSTRACT

Until recently, most studies report an increasing prevalence of allergy and asthma. The research suggests that the increase may have to do with changes in lifestyle and living conditions. This study seeks to determine the prevalence and changes in allergic diseases in relation to socioeconomic status (SES) 6 years apart. The research material consisted of data collected in two cross-sectional surveys conducted among university female students in 2009 and 2015 (respectively, 702 and 1305 subjects). The surveys evaluated the incidence of allergic conditions and socio-economic status. The occurrence of allergy was determined on the basis of answers to the questions whether the allergy and specific allergens were defined on the basis of medical work-up. The prevalence of allergic diseases increased from 14.0% to 22.3% over a 6-year period. In both cohorts, allergic diseases were more prevalent among females with high SES than with low SES. In 2009, significant differences were noted in relation to urbanization of the place of living and the number of siblings. In 2015, all socioeconomics factors significantly bore on the prevalence of allergy.


Subject(s)
Asthma/epidemiology , Hypersensitivity/epidemiology , Socioeconomic Factors , Cross-Sectional Studies , Female , Humans , Poland/epidemiology , Prevalence , Self Report , Students , Surveys and Questionnaires , Universities
2.
Homo ; 67(6): 498-507, 2016 Dec.
Article in English | MEDLINE | ID: mdl-27908489

ABSTRACT

One of the most severe detrimental environmental factors acting during pregnancy is foetal smoke exposure. The aim of this study was to assess the effect of maternal, paternal and parental smoking during pregnancy on relative leg length in 7- to 10-year-old children. The research conducted in the years 2001-2002 included 978 term-born children, 348 boys and 630 girls, at the age of 7-10 years. Information concerning the birth weight of a child was obtained from the health records of the women. Information about the mother's and the father's smoking habits during pregnancy and about the mothers' education level was obtained from a questionnaire. The influence of parental smoking on relative leg length, controlled for age, sex, birth weight and the mother's education, as a proxy measure of socioeconomic status, and controlled for an interaction between sex and birth weight, was assessed by an analysis of covariance, where relative leg length was the dependent variable, smoking and sex were the independent variables, and birth weight as well as the mother's education were the covariates. Three separate analyses were run for the three models of smoking habits during pregnancy: the mother's smoking, the father's smoking and both parents' smoking. Only both parents' smoking showed a significant effect on relative leg length of offspring. It is probable that foetal hypoxia caused by carbon monoxide contained in smoke decelerated the growth of the long bones of foetuses.


Subject(s)
Leg/pathology , Parents , Prenatal Exposure Delayed Effects/etiology , Prenatal Exposure Delayed Effects/pathology , Smoking/adverse effects , Child , Child Development , Educational Status , Female , Humans , Leg/growth & development , Male , Maternal Behavior , Paternal Behavior , Poland , Pregnancy , Tobacco Smoke Pollution/adverse effects
3.
Homo ; 66(3): 251-63, 2015 Jun.
Article in English | MEDLINE | ID: mdl-25618810

ABSTRACT

The neonatal line (NNL) is used to distinguish developmental events observed in enamel which occurred before and after birth. However, there are few studies reporting relationship between the characteristics of the NNL and factors affecting prenatal conditions. The aim of the study was to determine prenatal factors that may influence the NNL thickness in human deciduous teeth. The material consisted of longitudinal ground sections of 60 modern human deciduous incisors obtained from full-term healthy children with reported birth histories and prenatal factors. All teeth were sectioned in the labio-lingual plane using diamond blade (Buechler IsoMet 1000). Final specimens were observed using scanning electron microscopy at magnifications 320×. For each tooth, linear measurements of the NNL thickness were taken on its labial surface at the three levels from the cemento-enamel junction. The difference in the neonatal line thickness between tooth types and between males and females was statistically significant. A multiple regression analyses confirmed influence of two variables on the NNL thickness standardised on tooth type and the children's sex (z-score values). These variables are the taking of an antispasmodic medicine by the mother during pregnancy and the season of the child's birth. These two variables together explain nearly 17% of the variability of the NNL. Children of mothers taking a spasmolytic medicine during pregnancy were characterised by a thinner NNL compared with children whose mothers did not take such medication. Children born in summer and spring had a thinner NNL than children born in winter. These results indicate that the prenatal environment significantly contributes to the thickness of the NNL influencing the pace of reaching the post-delivery homeostasis by the newborn's organism.


Subject(s)
Tooth, Deciduous/anatomy & histology , Tooth, Deciduous/embryology , Child , Child, Preschool , Dental Enamel/anatomy & histology , Dental Enamel/drug effects , Dental Enamel/embryology , Female , Fetal Development/drug effects , Humans , Infant , Infant, Newborn , Male , Multivariate Analysis , Parasympatholytics/adverse effects , Pregnancy , Prenatal Exposure Delayed Effects , Seasons , Sex Characteristics , Tooth, Deciduous/drug effects
4.
Arch Oral Biol ; 58(8): 951-63, 2013 Aug.
Article in English | MEDLINE | ID: mdl-23583018

ABSTRACT

OBJECTIVE: Development of human tooth enamel is a part of a foetus's development; its correctness is the outcome of genetic and maternal factors shaping its prenatal environment. Many authors reported that individuals born in different seasons experience different early developmental conditions during pregnancy. In this study, we investigated the effects of season of birth and selected maternal factors on enamel thickness of deciduous incisors. DESIGN: Dental sample comprises 60 deciduous incisors. The parents who handed over their children's teeth for research fill in questionnaires containing questions about the course of pregnancy. All teeth were sectioned in the labio-linqual plane using diamond blade (Buechler IsoMet 1000). The final specimens were observed by way of scanning electron microscopy at magnifications 80× and 320×. The thickness of total enamel (TE), prenatally (PE) and postnatally (PSE) formed enamel was measured. RESULTS: Children born in summer and in spring (whose first and second foetal life fall on autumn and winter) have the thinnest enamel. Season of birth, number of children in family, diseases and spasmolytic medicines using by mother during pregnancy explained almost 13% of the variability of TE. Regression analysis proved a significant influence of the season of birth and selected maternal factors on the PE thickness - these factors explained over 17% of its variability. Neither of analysed variables had influenced PSE. CONCLUSIONS: Our findings suggests that the thickness of enamel of deciduous incisors depends on the season of birth and some maternal factors. The differences were observed only in the prenatally formed enamel.


Subject(s)
Dental Enamel/anatomy & histology , Incisor/anatomy & histology , Parturition/physiology , Seasons , Tooth, Deciduous/anatomy & histology , Amelogenesis/physiology , Birth Order , Child , Child, Preschool , Delivery, Obstetric , Dental Enamel/ultrastructure , Dietary Supplements/classification , Female , Gestational Age , Humans , Incisor/ultrastructure , Iron Compounds/therapeutic use , Male , Maternal Age , Microscopy, Electron, Scanning , Parasympatholytics/therapeutic use , Parity , Pregnancy , Pregnancy Complications , Self Report , Tooth, Deciduous/ultrastructure , Vitamins/therapeutic use
5.
Homo ; 63(3): 216-32, 2012 Jun.
Article in English | MEDLINE | ID: mdl-22608527

ABSTRACT

The aim of this study is to examine the prevalence of underweight, overweight and obesity, using International Obesity Task Force (IOTF) criteria, in four cohorts of children and adolescents living in Poland in different economic eras: communist economy (1977/1978), crisis of the 1980s (1987/1988), political and economic transformation (1992/1994) and the free market economy (2002/2004). Analysis was conducted on a database including 10,934 records for children of the age 7-18 years. In Poland, in the last 26 years of economic and political transformations, the epidemic of obesity was not noticed but the growing incidence of children and adolescents with body mass deficit was observed (p<0.0001) (20.2% of girls in 2002/2004 vs. 11.0% in 1977/1978 and 12.1% of boys in 2002/2004 vs. 7.2% in 1977/1978). Lower parental education and a higher number of children in a family resulted in a higher prevalence of underweight (odds ratio [OR] fluctuated from 1.26 to 1.63). The social effects of the political transformation in Poland significantly affected families with low socio-economic status (SES), and especially more eco-sensitive boys. This result is opposite to the trends observed in Western countries and makes an important contribution to the current knowledge of the course of further changes in weight-to-height ratio at a global scale.


Subject(s)
Overweight/epidemiology , Thinness/epidemiology , Adolescent , Child , Cohort Studies , Female , History, 20th Century , History, 21st Century , Humans , Male , Obesity/economics , Obesity/epidemiology , Obesity/history , Overweight/economics , Overweight/history , Poland/epidemiology , Politics , Social Class/history , Socioeconomic Factors/history , Thinness/economics , Thinness/history
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