ABSTRACT
BACKGROUND: Adjacent segment degeneration (ASD) has become a great concern as a late complication in patients following fusion spine surgery with a potential need for revision surgery. Segments above the fused spine have higher mobility and they are especially prone to accelerated disc degeneration. The purpose of our study is to investigate early disc degenerative changes two levels above a surgically fused lumbar spine segment and to compare MRI analyses after unilateral and bilateral TLIF procedures. METHODS: A total of 117 patients were included in this cross-sectional retrospective single center study (after bilateral TLIF surgery: n = 91, and after unilateral TLIF: n = 26). In both groups, the average patient age was similar: 62.84 years (SD = 12.53) in the unilateral TLIF group and 60.67 years (SD = 11.89) in the bilateral TLIF group. On average, MRI was performed 2.5 years after surgery (SD = 2.09). The modified eight-level Pfirrmann grading system was used for the assessment of disc degeneration severity. Descriptive statistics and the Mann-Whitney test were used to show differences in the Pfirrmann grades regarding the after-surgery period and the patient age. The Wilcoxon signed-rank test results were used to display differences in the Pfirrmann grades before and after surgery. RESULTS: The comparison of mean values, regardless of the type of surgery, shows that this mean value is on average higher in the first segment adjacent to the fused spine segment. The assessment of the intervertebral disc structure in BIL TLIF is higher in both the first and the second segment. Early disc degeneration progression is subtle yet detectable (UNI TLIF 9.28% vs. BIL TLIF 16.74%). The assessment of the intervertebral disc structure is on average lower in patients aged less than 50 years at time of surgery compared with patients aged more than 50 years in UNI TLIF, and higher in the BIL TLIF group, for both the first and the second segment. CONCLUSION: Patients who had undergone unilateral TLIF fusion surgery have a lower rate of early disc degenerative changes. Considering a significantly higher rate of progressive disc degenerative changes in the elderly with bilateral fusion surgery, extra caution is required in the selection of appropriate surgical technique.
ABSTRACT
BACKGROUND: Quantitative gait analysis is essential for evaluating walking and running patterns for markers of pathology, injury, or other gait characteristics. It is expected that the portability, affordability, and applicability of wearable devices to many different populations will have contributed advancements in understanding the real-world gait patterns of walkers and runners. Therefore, the purpose of this systematic review was to identify how wearable devices are being used for gait analysis in out-of-lab settings. METHODS: A systematic search was conducted in the following scientific databases: PubMed, Medline, CINAHL, EMBASE, and SportDiscus. Each of the included articles was assessed using a custom quality assessment. Information was extracted from each included article regarding the participants, protocol, sensor(s), and analysis. RESULTS: A total of 61 articles were reviewed: 47 involved gait analysis during walking, 13 involved gait analysis during running, and one involved both walking and running. Most studies performed adequately on measures of reporting, and external and internal validity, but did not provide a sufficient description of power. Small, unobtrusive wearable devices have been used in retrospective studies, producing unique measures of gait quality. Walking, but not running, studies have begun to use wearable devices for gait analysis among large numbers of participants in their natural environment. CONCLUSIONS: Despite the advantages provided by the portability and accessibility of wearable devices, more studies monitoring gait over long periods of time, among large numbers of participants, and in natural walking and running environments are needed to analyze real-world gait patterns, and would facilitate prospective, subject-specific, and subgroup investigations. The development of wearables-specific metrics for gait analysis provide insights regarding the quality of gait that cannot be determined using traditional components of in-lab gait analyses. However, guidelines for the usability of wearable devices and the validity of wearables-based measurements of gait quality need to be established.
