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1.
Sci Rep ; 11(1): 5622, 2021 03 10.
Article in English | MEDLINE | ID: mdl-33692489

ABSTRACT

Boiling is arguably Nature's most effective thermal management mechanism that cools submersed matter through bubble-induced advective transport. Central to the boiling process is the development of bubbles. Connecting boiling physics with bubble dynamics is an important, yet daunting challenge because of the intrinsically complex and high dimensional of bubble dynamics. Here, we introduce a data-driven learning framework that correlates high-quality imaging on dynamic bubbles with associated boiling curves. The framework leverages cutting-edge deep learning models including convolutional neural networks and object detection algorithms to automatically extract both hierarchical and physics-based features. By training on these features, our model learns physical boiling laws that statistically describe the manner in which bubbles nucleate, coalesce, and depart under boiling conditions, enabling in situ boiling curve prediction with a mean error of 6%. Our framework offers an automated, learning-based, alternative to conventional boiling heat transfer metrology.

2.
Sci Rep ; 7(1): 15259, 2017 11 10.
Article in English | MEDLINE | ID: mdl-29127385

ABSTRACT

Fabricated tissue phantoms are instrumental in optical in-vitro investigations concerning cancer diagnosis, therapeutic applications, and drug efficacy tests. We present a simple non-invasive computational technique that, when coupled with experiments, has the potential for characterization of a wide range of biological tissues. The fundamental idea of our approach is to find a supervised learner that links the scattering pattern of a turbid sample to its thickness and scattering parameters. Once found, this supervised learner is employed in an inverse optimization problem for estimating the scattering parameters of a sample given its thickness and scattering pattern. Multi-response Gaussian processes are used for the supervised learning task and a simple setup is introduced to obtain the scattering pattern of a tissue sample. To increase the predictive power of the supervised learner, the scattering patterns are filtered, enriched by a regressor, and finally characterized with two parameters, namely, transmitted power and scaled Gaussian width. We computationally illustrate that our approach achieves errors of roughly 5% in predicting the scattering properties of many biological tissues. Our method has the potential to facilitate the characterization of tissues and fabrication of phantoms used for diagnostic and therapeutic purposes over a wide range of optical spectrum.

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