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2.
J Craniofac Surg ; 30(3): 663-666, 2019.
Article in English | MEDLINE | ID: mdl-30507877

ABSTRACT

This article presents the case of a newly born female patient with a cleft of the primary palate (alveolar cleft), with an in utero diagnosis of the described cleft, from whom umbilical cord stem cells are obtained and cryopreserved. The patient is managed with nasoalveolar molding, and at 5 months of age, she is taken to surgery for cheiloplasty and gingivoperiostioplasty with umbilical cord stem cells. A radiographic and CT follow-up is carried out on the described cleft.


Subject(s)
Cleft Palate/surgery , Cord Blood Stem Cell Transplantation/methods , Orthognathic Surgical Procedures/methods , Female , Humans , Infant
3.
Ann Plast Surg ; 79(3): 293-297, 2017 Sep.
Article in English | MEDLINE | ID: mdl-28737553

ABSTRACT

INTRODUCTION: Over recent years, body contouring procedures in postbariatric patients have been in exponentially growing demand resulting in high complication rates rendering a variety of ciphers in the literature. OBJECTIVE: The purpose of this study is to determine the complication rate in patients who have undergone body contouring surgery after bariatric surgery between June 2012 and March 2015 at Hospital de San José. METHODS: A cohort study including 153 individuals who underwent a total of 198 body contouring procedures after massive weight loss following bariatric surgery was conducted. Data on variables, such as complication rate according to the type of body contouring surgery, major and minor complications, weight of resected tissue, or intraoperation time, among other variables, were analyzed. RESULTS: A total of 198 procedures were performed in 153 patients. The mean (SD) age of the patients was 43.93 years (9.4 years). Of 198 procedures, 110 (55.5%) had complications. The rate for major complications was 13%, and for minor complications, 87%. Complication rates according to the type of operation were as follows: circumferential abdominal lipectomy, 55.7%; extended abdominal lipectomy, 53.7%; cruroplasty, 69%; breast surgery, 57%; and brachioplasty, 40%. Patients who presented with bleeding enough to require transfusion (P = 0.000) and with weight of the resected tissue greater than 2700 g in abdominoplasty (odds ratio, 3.26; 95% confidence interval, 1.48-7.1) had a higher complication rate. There were no thromboembolic events among this population. CONCLUSIONS: The overall complication rate was 55.5%. The great majority were minor complications. The thromboprophylaxis regimen used was 100% effective.


Subject(s)
Abdominoplasty/adverse effects , Bariatric Surgery/adverse effects , Body Contouring/adverse effects , Postoperative Complications/epidemiology , Abdominoplasty/statistics & numerical data , Adult , Bariatric Surgery/methods , Body Contouring/statistics & numerical data , Body Mass Index , Cohort Studies , Colombia , Female , Humans , Male , Middle Aged , Obesity, Morbid/surgery , Postoperative Complications/prevention & control , Risk Assessment , Risk Factors , Weight Loss
4.
Acta méd. colomb ; 33(4): 261-267, dic. 2008. graf, tab
Article in Spanish | LILACS | ID: lil-635275

ABSTRACT

El hígado es el principal órgano que sirve de primer paso en la biotransformación de la mayoría de los medicamentos, los cuales en algunos casos pueden conllevar a toxicidad hepática, debido a la acción tóxica directa y/o factores idiosincráticos. El diagnóstico suele ser difícil y por ello se han establecido escalas para evaluar daño hepático inducido por medicamentos. El objetivo de nuestro estudio consiste en describir las características clínicas, bioquímicas y epidemiológicas de los casos de hepatotoxicidad medicamentosa documentadas en las historias clínicas de los pacientes evaluados por la unidad de hepatología de un hospital de cuarto nivel en la ciudad de Medellín, Hospital Pablo Tobón Uribe (HPTU), entre enero 2001 y enero 2008. Se presenta un análisis estadístico de 42 casos de hepatotoxicidad medicamentosa atribuida a fármacos como los antibióticos, inmunosupresores, anticonvulsivantes, analgésicos, entre otros. Todos fueron evaluados por la escala de daño hepático inducida por medicamentos y tuvieron desenlaces como hepatitis aguda, falla hepática, trasplante, etc.


The liver is the main first-step organ involved in the metabolism of most medications. Therefore it is vulnerable to drug toxicity in some cases, due to direct toxic action and/or to idiosyncratic factors. The diagnosis is usually difficult; therefore there are some scales whose purpose is to assess hepatic damage induced by drugs. The objective of our study is to describe the clinical, biochemical and epidemiological characteristics of cases of hepatotoxicity documented in the case histories of patients evaluated by the hepatology unit of a fourth-level hospital in the city of Medellin, Hospital Pablo Tobón Uribe (HPTU), between January 2001 and January 2008. A statistical analysis is presented of 42 cases of liver toxicity ascribed to drugs such as antibiotics, immunosuppressants, antiepileptics, and analgesics, among others. All were evaluated using the scale of hepatic damage induced by medications, and they had outcomes like acute hepatitis, hepatic failure, transplant, etc.

5.
Iatreia ; 20(1): 64-73, mar. 2007. tab, graf
Article in Spanish | LILACS | ID: lil-453829

ABSTRACT

El cáncer primario de hígado es en el mundo la quinta neoplasia más común en hombres y la octava en mujeres, con gran impacto debido a su alta mortalidad, ya que representa la tercera causa de mortalidad relacionadacon cáncer en población masculina. Se ha descrito una fuerte asociación con factores de riesgo como las hepatitis virales crónicas, las hepatopatías de origengenético, el consumo de alcohol, el tabaquismo y enfermedades metabólicas, entre otras. En este artículo se analizan publicaciones originales y de revisión en las que se evalúan dichos factores y su asociación con el carcinoma hepatocelular (CHC).Además, se recopila información actualizada sobre datos epidemiológicos por regiones del mundo.


Subject(s)
Aflatoxins/adverse effects , Carcinoma, Hepatocellular , Diabetes Mellitus , Ethanol , Risk Factors , Hepacivirus , Hepatitis B virus , Epidemiology , Liver Diseases/genetics , Obesity , Nicotiana
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