ABSTRACT
The coexistence of systemic lupus erythematosus (SLE) and ANCA-associated vasculitis (AAV) as an overlapping syndrome is not common. Here, we report a case of a 33-year-old woman, with recent SLE diagnosis due to skin, kidney, articular, and immunologic compromise, in whom a chest CT scan showed bilateral nodules, consolidations, and tree-in-bud pattern; thoracoscopic lung biopsy revealed diffuse non-caseating granulomas, without other features of sarcoid, organizing pneumonia, or hypersensitivity pneumonitis with high positive p-ANCA titers. Overlap between SLE and AAV was a possible explanation for lupus granulomatous pneumonitis, and for this reason, a multidisciplinary meeting was held to evaluate complex patients with interstitial lung diseases patients.
Subject(s)
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis , Lung Diseases, Interstitial , Lupus Erythematosus, Discoid , Lupus Erythematosus, Systemic , Adult , Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/complications , Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/diagnosis , Female , Humans , Kidney/pathology , Lung Diseases, Interstitial/complications , Lupus Erythematosus, Discoid/pathology , Lupus Erythematosus, Systemic/complications , Lupus Erythematosus, Systemic/diagnosisABSTRACT
Resumen Revisión narrativa sobre cómo el cáncer altera la fisiología de la pleura, cómo se estudia el derrame pleural maligno y cómo se puede brindar paliación al paciente con derrame pleural mediante el catéter pleural permanente tunelizado, cuyo uso demuestra mayores beneficios en diferentes ámbitos clínicos, siendo utilizado principalmente para el tratamiento del derrame pleural tumoral recurrente, pero también en algunos casos de derrame pleural benigno repetitivo, convirtiéndolo en un recurso terapéutico útil en el cáncer avanzado.
Abstract This narrative review examines how cancer causes changes in pleural physiology, how to study malignant pleural effusion, and how to bring palliative care to patients with pleural effusion by means of indwelling tunneled pleural catheter. This catheter shows greater benefits in clinical practice, being used mainly for the treatment of recurrent malignant pleural effusion, but also in some cases of recurrent benign pleural effusion, making it a useful therapeutic tool in advanced cancer.
