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1.
Vopr Onkol ; 30(3): 40-4, 1984.
Article in Russian | MEDLINE | ID: mdl-6710947

ABSTRACT

A complex morphologic procedure for evaluating the effect of synthetic progestin treatment in 136 cases of primary endometrial cancer was analysed. Changes in structural and functional characteristics of tumor testifying to the elevated degree of cell differentiation were observed in 89.7 +/- 6.4 per cent of cases of well- and moderately-differentiated endometrial cancer. In glandular-solid cancer group, the response was registered in 52.6 +/- 11.5 per cent and manifested itself in tumor showing the same changes coupled with an increase in glandular structures, or developing squamous metaplasia in solid areas. Hormonal effects following hydroxyprogesterone capronate treatment were found in 81.8 +/- 11.6% of adenoacanthocarcinoma patients.


Subject(s)
Adenocarcinoma/pathology , Carcinoma, Squamous Cell/pathology , Hydroxyprogesterones/therapeutic use , Uterine Neoplasms/pathology , 17 alpha-Hydroxyprogesterone Caproate , Adenocarcinoma/drug therapy , Adenocarcinoma/surgery , Biopsy , Carcinoma, Squamous Cell/drug therapy , Carcinoma, Squamous Cell/surgery , Combined Modality Therapy , Female , Humans , Neoplasm Recurrence, Local/prevention & control , Time Factors , Uterine Neoplasms/drug therapy , Uterine Neoplasms/surgery
2.
Arkh Patol ; 39(3): 56-63, 1977.
Article in Russian | MEDLINE | ID: mdl-871256

ABSTRACT

Cytograms of various histologically established forms of cancer of cervix uteri in 114 patients were analysed. The data obtained were used in subsequent collations of cytological and histological diagnoses of cervix uteri cancer in 550 patients. It was established that in a cytological investigation it was possible to determine the histological structure of tumours in 84.2% of the cases. Squamous cell keratinizing carcinoma could be diagnosed cytologically in 97.7%, squamous cell nonkertinizing carcinoma--in 74.7%, adenocarcinoma--in 84.1%, low differentiated--in 50% of the observations.


Subject(s)
Adenocarcinoma/diagnosis , Carcinoma, Squamous Cell/diagnosis , Uterine Cervical Neoplasms/diagnosis , Adenocarcinoma/metabolism , Adenocarcinoma/pathology , Carcinoma, Squamous Cell/metabolism , Carcinoma, Squamous Cell/pathology , Cell Nucleus/ultrastructure , Cytodiagnosis , DNA, Neoplasm/metabolism , Female , Glycogen/metabolism , Histocytochemistry , Humans , RNA, Neoplasm/metabolism , Uterine Cervical Neoplasms/metabolism , Uterine Cervical Neoplasms/pathology
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