Subject(s)
Accidental Falls/prevention & control , Health Promotion , Postural Balance/physiology , Academic Medical Centers , Accidental Falls/economics , Aged , Aged, 80 and over , Aging/physiology , Biomedical Research , Cost of Illness , Female , Fractures, Bone/economics , Fractures, Bone/etiology , France , Geriatrics/education , Humans , Independent Living , Information Dissemination , Male , Public Health , Risk FactorsABSTRACT
Calf vein thrombosis corresponds to infrapopliteal deep vein thrombosis which accounts for roughly 50% of all cases of deep vein thrombosis and shares the same risk factors as proximal deep vein thrombosis. The complication rate and proper management remain debated. Recent studies suggest that the risk of proximal extension of calf vein thrombosis is 1 to 5% and that the risk of postthrombotic syndrome is 3%. In France, calf vein thrombosis is usually treated with compression stockings associated with a six week to three month regimen of anticoagulation therapy in patients presenting a transient triggering factor or longer otherwise. However, the benefit of such treatment, in terms of the hemorragic risk incurred, remains uncertain. The randomized double blind trial CACTUS (compression stocking + placebo versus compression stocking + heparin, for six weeks) that will start in September 2007, should provide answers the following question: should calf vein thrombosis be treated with anticoagulants?
Subject(s)
Leg/blood supply , Venous Thrombosis/epidemiology , Venous Thrombosis/therapy , Anticoagulants/therapeutic use , France/epidemiology , Humans , Popliteal Vein , Randomized Controlled Trials as Topic , Risk Factors , Stockings, Compression , Venous Thrombosis/complicationsSubject(s)
Amyloidosis/diagnostic imaging , Kidney/abnormalities , Peritoneal Diseases/diagnostic imaging , Adenocarcinoma/complications , Adenocarcinoma/surgery , Aged , Amyloidosis/complications , Biopsy , Diagnosis, Differential , Hematuria/etiology , Humans , Male , Peritoneal Diseases/complications , Retroperitoneal Space , Sigmoid Neoplasms/complications , Sigmoid Neoplasms/surgery , Tomography, X-Ray Computed , UrographyABSTRACT
Cowden's Disease is an autosomal dominant genodermatosis associated with abnormalities of the breast, thyroid gland, gastrointestinal tract. We describe a 23-year-old girl who was diagnosed with this disease when she consulted for evaluation of a multinodular goiter. Further investigations revealed breast lesions, gastric polyposis and parotid cancer. Recognizing Cowden's disease is important for prompt screening for malignancies. Skin lesions are markers of precancerous development.
