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2.
Arch Pediatr ; 3(3): 267-73, 1996 Mar.
Article in French | MEDLINE | ID: mdl-8785567

ABSTRACT

Acute encephalitis is mainly of viral origin. Two groups of are considered: i) primary encephalitis, such as Herpes simplex encephalitis with intra-thecal synthesis of antibodies, and ii) post-viral infection encephalitis or acute disseminated encephalitis with immune dysregulation. The most common clinical presentation (fever, consciousness disturbance and seizures) is not specific and may reveal bacterial meningitis or cerebral abscess which require a specific treatment. Acyclovir has allowed consistant advances in the treatment of herpes encephalitis. Vaccination against selected viral infection, such as measle vaccine, is the only way to prevent acute disseminated encephalitis.


Subject(s)
Encephalitis , Acute Disease , Child , Child, Preschool , Encephalitis/diagnosis , Encephalitis/etiology , Encephalitis/pathology , Encephalitis/therapy , Encephalitis, Viral/diagnosis , Herpes Simplex/diagnosis , Humans , Infant , Measles/complications
8.
Ann Pediatr (Paris) ; 37(6): 409-10, 1990 Jun.
Article in French | MEDLINE | ID: mdl-2400195

ABSTRACT

We report a new case of Kocher-Debré-Semelaigne syndrome in a child and describe this condition on the basis of a review of the literature. Affected individuals exhibit both hypothyroidism and pseudohypertrophic myopathy and consequently have an athletic appearance that contrasts with physical and psychological sluggishness.


Subject(s)
Genetic Diseases, Inborn/diagnosis , Hypothyroidism/diagnosis , Muscular Diseases/diagnosis , Child, Preschool , Genetic Diseases, Inborn/pathology , Genetic Diseases, Inborn/physiopathology , Humans , Hypertrophy , Hypothyroidism/pathology , Hypothyroidism/physiopathology , Male , Muscles/pathology , Muscular Diseases/pathology , Muscular Diseases/physiopathology
9.
Ann Pediatr (Paris) ; 37(5): 331-3, 1990 May.
Article in French | MEDLINE | ID: mdl-1973341

ABSTRACT

We report a new case of strictly cutaneous periarteritis nodosa in a girl aged 5 1/2 years at onset of the disease. No visceral involvement has developed during the seven years follow-up. Our patient is the fourth published pediatric case of strictly cutaneous periarteritis nodosa.


Subject(s)
Polyarteritis Nodosa , Skin Diseases , Child, Preschool , Female , Follow-Up Studies , Humans , Muscles/pathology , Polyarteritis Nodosa/pathology , Skin/pathology , Skin Diseases/pathology
12.
Pediatrie ; 45(1): 21-3, 1990.
Article in French | MEDLINE | ID: mdl-2158044

ABSTRACT

Lissencephaly is a rare brain anomaly characterized by a lack of cerebral sulci and gyri. We report 2 cases of lissencephaly syndrome with infantile spasms diagnosed by CT-Scan. We discuss the relationship between lissencephaly and infantile spasms, and attempt to estimate the frequency of infantile spasms in lissencephaly and the frequency of this cerebral abnormality among other etiologies of infantile spasms. The prognosis of infantile spasms is indeed variable, according to the presence of underlying cerebral abnormality.


Subject(s)
Brain/abnormalities , Cerebral Cortex/abnormalities , Spasms, Infantile/complications , Female , Humans , Infant , Male
13.
Presse Med ; 18(34): 1699-700, 1989 Oct 21.
Article in French | MEDLINE | ID: mdl-2577026

ABSTRACT

Bone involvement has exceptionally been reported in children with periarteritis nodosa. A 5-year old girl was admitted to hospital for fever and arthralgias. Three months later, myalgias and painful subcutaneous nodules developed on the legs and ankles. Skin biopsy yielded a diagnosis of periarteritis nodosa. X-ray films revealed a bilateral periosteal reaction with images of laminae in the tibia and fibula. After a 4-year remission under corticosteroid therapy, the periosteal reaction persisted.


Subject(s)
Periosteum/pathology , Polyarteritis Nodosa/pathology , Ankle , Arthritis, Rheumatoid/pathology , Child, Preschool , Female , Humans , Leg , Tibia/pathology
16.
Arch Fr Pediatr ; 43(5): 331-3, 1986 May.
Article in French | MEDLINE | ID: mdl-3490837

ABSTRACT

In a 13 year-old boy treated for polyarthritis, nephrocalcinosis and an inability to acidify urine were observed. Distal renal tubular acidosis may be associated with articular manifestations and is reversible with the usual treatment with alkali as are the other manifestations of the disease.


Subject(s)
Acidosis, Renal Tubular/diagnosis , Rheumatic Diseases/diagnosis , Acidosis, Renal Tubular/complications , Adolescent , Arthritis/diagnosis , Arthritis/etiology , Humans , Male , Nephrocalcinosis/complications , Nephrocalcinosis/diagnosis , Rheumatic Diseases/etiology
17.
Arch Fr Pediatr ; 40(5): 415-9, 1983 May.
Article in French | MEDLINE | ID: mdl-6411042

ABSTRACT

68 epileptic children were treated with carbamazepine (CBZ) monotherapy for a mean period of 10 months. The seizures disappeared in 43% and decreased in another 26.5% of cases. The treatment was particularly efficient in partial benign epilepsies (disappearance: 64.7%, reduction: 29.4%) and in partial unclassifiable epilepsies (disappearance: 50%, reduction: 25%). It is sometimes useful to achieve blood levels over 4 micrograms/ml; but over 8 micrograms/ml the frequency of side-effects becomes greater than improvement of fit frequency. The dose-concentration relation is well correlated to age, so that blood level measurements do not need to be systematically performed. In order to obtain mean blood levels of 7 micrograms/ml 3 to 4 hours after morning intake, mean daily dose should range from: 20 mg/kg/24 h before 5 years to 10 mg/kg/24 h after 10 years.


Subject(s)
Carbamazepine/therapeutic use , Epilepsy/drug therapy , Adolescent , Adult , Carbamazepine/adverse effects , Carbamazepine/blood , Child , Child, Preschool , Dose-Response Relationship, Drug , Epilepsies, Partial/drug therapy , Epilepsy/blood , Female , Humans , Infant , Male
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