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1.
Rev Med Interne ; 31(3): 229-31, 2010 Mar.
Article in French | MEDLINE | ID: mdl-20079561

ABSTRACT

INTRODUCTION: Neuroborreliosis can be a difficult diagnosis which requires epidemiologic, clinical and biologic arguments. CASE REPORTS: We report two patients who presented with a recurrent laryngeal nerve palsy with positive Lyme serology and favorable outcome after antibiotic therapy. In one case, a lymphocytic meningitis with intrathecal production of specific antibodies was evidenced. CONCLUSION: Recurrent laryngeal nerve palsy is an uncommon manifestation of neuroborreliosis. Lyme serology is an important tool when neurologic disorder occurs because of an atypical course of Lyme disease.


Subject(s)
Borrelia burgdorferi/isolation & purification , Lyme Neuroborreliosis/complications , Lyme Neuroborreliosis/diagnosis , Vocal Cord Paralysis/diagnosis , Vocal Cord Paralysis/microbiology , Aged, 80 and over , Anti-Bacterial Agents/therapeutic use , Female , Humans , Lyme Disease/complications , Lyme Disease/diagnosis , Lyme Neuroborreliosis/drug therapy , Male , Middle Aged , Sensitivity and Specificity , Serologic Tests , Treatment Outcome , Vocal Cord Paralysis/drug therapy
2.
Rev Med Interne ; 27(7): 550-4, 2006 Jul.
Article in French | MEDLINE | ID: mdl-16750284

ABSTRACT

INTRODUCTION: The granulomatous mastitis is an inflammatory pseudotumor of the breast of which evolution benign but likely to generate important morphological after-effects among young women. This anatomoclinic entity of dubious etiology until these last years poses a problem of differential diagnosis with other etiologies of granulomatosis and especially with inflammatory carcinoma of the breast. The infectious theory is actually based on solid arguments and mainly explains the physiopathology of this affection. INTERPRETATION: A 26 years old young woman developed an inflammatory tumor of the left breast of which the catch of load by surgery and an antibiotherapy had shown trailing local continuations and of the esthetic after-effects. One year later, a very inflammatory repetition on the level of the right breast was dealt with in a different way: by steroids and immunomodulating drugs associated with iterative punctures with the purulent collections, the objective being to be less dilapidating that left side. The initial answer was rather favorable and encouraging but the purulent reappearance bulky granulomas with sinus way made reconsider the therapeutic attitude and antibiotics were undertaken after description of a lipophilic corynebactery in the material of puncture (Corynebacteria kroppenstedtii). The effectiveness of the amoxicilline introduced on the data of the antibiogram was undeniable. CONCLUSION: This observation illustrates the therapeutic and diagnostic difficulties of an exceptional affection. Potentially accessible to antibiotics it generally requires a joint surgical assumption of responsibility, at the same time to ensure the histological diagnosis but also with a therapeutic aim. The interest of steroids and the immunomodulation by methotrexate is debatable, these treatments cannot however be conceived without antibiotherapy and sometimes surgery.


Subject(s)
Corynebacterium Infections/diagnosis , Granuloma, Plasma Cell/microbiology , Mastitis/microbiology , Adult , Amoxicillin/therapeutic use , Anti-Bacterial Agents/therapeutic use , Corynebacterium/classification , Corynebacterium/isolation & purification , Diagnosis, Differential , Female , Glucocorticoids/therapeutic use , Granuloma, Plasma Cell/diagnosis , Humans , Immunosuppressive Agents/therapeutic use , Mastitis/diagnosis , Methotrexate/therapeutic use , Prednisone/therapeutic use , Punctures , Recurrence
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