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Tunis Med ; 85(5): 393-7, 2007 May.
Article in French | MEDLINE | ID: mdl-17657925

ABSTRACT

Acute myeloid leukemia (AML)'s diagnosis is clinical and biological. We report here 80 AML with cytology and immunophenotype features to establish correlations. 21 AML1, 23 AML2, 12 AML3, 2 AML4, 18 AML5 and 3 AML6 were diagnosed by cytology. Only one case of AML0 was diagnosed by immunophenotype. Myelogysplasia is present in 29.8% cases. CD19 and CD56 expression was significantly associated to AML +t(8;21). Additionally, concomitant negativity of CD34 and HLA-DR was discrimininatif to AML3 diagnosis. Prognostic value to expression some CD needs time backwards.


Subject(s)
Leukemia, Myeloid, Acute/pathology , Adolescent , Adult , Antigens, CD19/analysis , Antigens, CD34/analysis , B-Lymphocytes/pathology , CD56 Antigen/analysis , Child , Child, Preschool , Female , HLA-DR Antigens/analysis , Humans , Immunohistochemistry , Immunophenotyping , Leukemia, Myeloid, Acute/classification , Leukemia, Myeloid, Acute/immunology , Male , Middle Aged , Myelodysplastic Syndromes/immunology , Myelodysplastic Syndromes/pathology , Myeloid Cells/pathology , Peroxidase/analysis , Prognosis , T-Lymphocytes/pathology
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