ABSTRACT
To determine the role and importance of beta-haemolytic streptococci in acute pharyngitis and its relative susceptibility to antibiotics, we cultured samples from 143 patients (age range: 3-72 years) who presented over a 5-month period in 2001 at three primary health care centres in Sousse, Tunisia. The cultures yielded 80 beta-haemolytic streptococci (59 group A streptococci and 21 non-group A streptococci). All strains were susceptible to benzylpenicillin, amoxicillin, chloramphenicol, rifampicin and pristinamycin. Susceptibility was variable in erythromycin, tetracycline, fosfomycin, telithromycin and levofloxacin. Minimum inhibitory concentrations were determined by E-test for penicillin, erythromycin and levofloxacin. Our results confirm that penicillin is still the reference treatment for acute pharyngitis. However, to minimize the potential for complications arising from its use, continued vigilance is required.
Subject(s)
Pharyngitis/microbiology , Streptococcal Infections/complications , Streptococcus pyogenes , Acute Disease , Adolescent , Adult , Age Distribution , Aged , Anti-Bacterial Agents/therapeutic use , Child , Child, Preschool , Drug Resistance, Bacterial , Humans , Incidence , Microbial Sensitivity Tests , Middle Aged , Patient Selection , Population Surveillance , Prevalence , Streptococcal Infections/drug therapy , Streptococcal Infections/epidemiology , Streptococcal Infections/microbiology , Tunisia/epidemiologyABSTRACT
Staphylococci remain among the main responsible bacteria for septicemia. The resistance to antibiotics already makes a prognosis difficult. We carried out a study on Staphylococcus isolated from blood culture on 3 years in general hospital in Tunisia. We present the different species and their sensitivity to antibiotics. S. aureus is the predominant isolated species. S. epidermidis is essentially isolated in newborn intensive care unit. The meticillino-resistance concerns 14% of the whole strains and 5.2 of the S. aureus. No resistance is found as regard the vancomycin and the pristinamycin; ofloxacine is inactive on 14.8% of strains and the gentamicine on 11.3%. The resistance of staphylococci of our study is lower than the rates reported in southern Europe and in North America.
Subject(s)
Bacteremia/microbiology , Hospitals, General , Staphylococcal Infections/microbiology , Staphylococcus/classification , Staphylococcus/drug effects , Drug Resistance, Microbial , Humans , Infant, Newborn , Microbial Sensitivity Tests , Staphylococcus/isolation & purification , Staphylococcus aureus/drug effects , Staphylococcus aureus/isolation & purification , Staphylococcus epidermidis/drug effects , Staphylococcus epidermidis/isolation & purification , TunisiaABSTRACT
To determine the role and importance of beta-haemolytic streptococci in acute pharyngitis and its relative susceptibility to antibiotics, we cultured samples from 143 patients [age range: 3-72 years] who presented over a 5-month period in 2001 at three primary health care centres in Sousse, Tunisia. The cultures yielded 80 beta-haemolytic streptococci [59 group A streptococci and 21 non-group A streptococci]. All strains were susceptible to benzylpenicillin, amoxicillin, chloramphenicol, rifampicin and pristinamycin. Susceptibility was variable in erythromycin, tetracycline, fosfomycin, telithromycin and levofloxacin. Minimum inhibitory concentrations were determined by E-test for penicillin, erythromycin and levofloxacin. Our results confirm that penicillin is still the reference treatment for acute pharyngitis. However, to minimize the potential for complications arising from its use, continued vigilance is required
Subject(s)
Acute Disease , Age Distribution , Anti-Bacterial Agents , Child, Preschool , Drug Resistance, Bacterial , Incidence , Microbial Sensitivity Tests , Patient Selection , Streptococcal Infections , PharyngitisABSTRACT
Current bacteriological data are very useful when making therapeutic decisions in cases of non complicated urinary tract infection. In this article, we present the data gathered by a university hospital laboratory in mid-Tunisia as well as the results of 17,829 urinary cytobacteriological examinations conducted in a multidisciplinary hospital during the year 2000. Urine was sowed on usual agar. All bacterium cultivating at least 10(5) bacteria reported to ml and at 37 degrees C in a normal atmosphere was retained; identification and sensitivity to antibiotics of the bacterium followed the recommendations of the French Society of Microbiology. We collected 2063 non-redundant bacteria of which 82.3% came from female samples. Gram negative rods were distinctly predominant with 92% of the whole bacterium and Escherichia coli represented 67% of the whole of the germs; Staphylococcus saprophyticus with 4.8% and Streptococcus agalactiae with 1% dominated Gram positive bacteria. The susceptibility of bacteria to the principal antibiotics used for the treatment of the urinary tract infection was characterised by the low percentage of sensitivity of the Gram negative rods to amoxicillin (41.2% of sensitivity for Escherichia coli and 22% for the Proteus sp), and by cotrimoxazole which preserved an activity between 63.8% for Escherichia coli and 94.7% for Staphylococcus saprophyticus. The highest percentage of sensitivity was achieved by gentamicine (99.4% of Escherichia coli and 98.9% of Staphylococcus saprophyticus) and fluoroquinolons (97.8% of Escherichia coli and 100% of Staphylococcus saprophyticus are sensible); furadoin was active on almost all Escherichia coli and Staphylococcus saprophyticus. Apart from natural resistance, colistin was constantly active. Escherichia coli and Staphylococcus saprophyticus were the major agents of the urinary tract infection. Gentamicin and fluoroquinolons showed themselves to be constantly active antibiotics. Nitrofurans and colistin deserve a better place in therapeutic choice.