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Pan Afr Med J ; 36: 165, 2020.
Article in English | MEDLINE | ID: mdl-32952809

ABSTRACT

Pre-extensively drug resistant tuberculosis (pre-XDR-TB) has been an area of growing concern, and posing a threat to global efforts of TB control. We report a case of PreXDR-TB spondylodiscitis with resistance to a Fluoroquinolone, in an immunocompetent patient under antibacillary treatment for pleural tuberculosis, managed with drug sensitivity-based second-line antituberculous drug regimen. Our case shows the challenges of the diagnostic and management of Drug-resistant TB spondylodiscitis.


Subject(s)
Antitubercular Agents/pharmacology , Discitis/drug therapy , Extensively Drug-Resistant Tuberculosis/drug therapy , Tuberculosis, Pleural/drug therapy , Adult , Discitis/diagnosis , Discitis/microbiology , Drug Resistance, Multiple, Bacterial , Extensively Drug-Resistant Tuberculosis/diagnosis , Extensively Drug-Resistant Tuberculosis/microbiology , Fluoroquinolones/pharmacology , Humans , Male , Microbial Sensitivity Tests , Mycobacterium tuberculosis/drug effects , Mycobacterium tuberculosis/isolation & purification , Tuberculosis, Multidrug-Resistant/drug therapy , Tuberculosis, Multidrug-Resistant/microbiology , Tuberculosis, Pleural/microbiology
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