[Peripheral and bone marrow hematological modifications in infection by the human immunodeficiency virus (HIV) in central Africa. Diagnostic and prognostic significance]. / Modifications hématologiques périphériques et médullaires lors de l'infection par le virus de l'immunodéficience humaine (VIH) en Afrique Centrale. Intérêt diagnostic et pronostic.

From the 24 March 1988 to the 15 June 1989, we noticed the peripheric and medullar haematologic modifications of 46 patients infected by HIV, classified in the group IV of CDC. The haematologic modifications found are: a peripheric cytopenia with a constant anemia often serious, a leuconeutropenia, a mild or missing lymphopenia. In comparison: the bone marrow is often rich in the different lineage with more often a sharp lymphoplasmocytal reaction, sometime very characteristic on the cytological side. 2 myeloid leukemia were diagnosed by participation of the myelogram. At least, the proteinogram showed a major polyclonal hypergammaglobulinemy sometimes monoclonal.

[Hematologic parameters during human immunodeficiency virus (HIV) infection in various Congolese subpopulations]. / Etude de paramètres hématologiques au cours de l'infection par le virus de l'immunodéficience humaine (VIH) dans différentes sous-populations Congolaises.

Study of 220 haematological profiles in women, men and children was realized in National Laboratory of Public Health and in Central Army Hospital in Brazzaville. The red cells count the haemoglobin level, the leucocytes and eosinophilia leukocyte counts in each sub-group of HIV+ and HIV- patients were compared. The anemia is important in HIV+ patients (Center for Diseases Control IV). The hyperleukocytosis and lymphocytosis of child and lymphopenia of adult are confirmed. The interest of surveillance of haematological parameters is as important for HIV+ asymptomatic individuals (Center for Diseases Control II) as for those of Center for Diseases Control IV group. The study of haematological profile is the interesting factor of diagnostic and prognosis.

[Histoplasma capsulatum histoplasmosis. Apropos of a disseminated form with skin lesions in a woman from Zaire]. / Histoplasmose à Histoplasma capsulatum. A propos d'une forme disséminée avec localisation cutanée chez une Zaïroise.

A case of disseminated histoplasmosis with cutaneous lesions due to Histoplasma capsulatum is reported. The patient was a 22 years old congolese woman (Zaïre). The diagnosis was made on born narrow a few days only before she died. The cutaneous lesions were also positive for H. capsulatum.