Intracranial epidermoid cysts: benign entities with malignant behavior: experience with 36 cases.

Intracranial epidermoid cysts are benign slow-growing ectodermal inclusions that account for less than 1% of all intracranial tumors. We retrospectively reviewed 36 such cases to evaluate the demographic characteristics, clinical manifestations, anatomical distribution, surgical management, and treatment outcome of these tumors. Additionally, we sought to identify the relationship between median or paramedian cistern tumor localization and clinical parameters, such as recurrence risk, hospitalization duration, and postoperative complication rates. The most frequently observed neurological symptoms were transient headaches (77.8%), dizziness (36.1%), CN VII palsy (19.4%), CN VIII hearing difficulty (19.4%) and cerebellar signs (19.4%). The most common surgical approaches included retrosigmoid (36.1%), subfrontal (19.4%) and telovelar (19.4%) approaches; gross total resection was feasible in 83.3% of cases. The postoperative complication rate was 38.9%. Tumors were more frequently found in the paramedian cisterns (47.2%), followed by the median line cisterns (41.6%). Multivariate analysis revealed that postoperative hydrocephalus and age < 40 years were prognostic factors for tumor recurrence. Median-like tumor location was a risk factor for the presence of symptomatic hydrocephalus both preoperatively and postoperatively, increasing the likelihood of protracted hospitalization (> 10 days). Despite their benign histopathological nature, these tumors have an important clinical resonance, with a high rate of postoperative complications and a degree of recurrence amplified by younger age and hydrocephalus.

Safety of Anterior Cervical Disc Arthroplasty in the Ambulatory Setting: an Eastern European Experience.

Aim: Spine surgery has been gradually transitioning from the inpatient setting into ambulatory surgery centers (ASC) and as such, the safety of treating patients on an outpatient basis needs to be validated. Objective:In this study, we aimed to evaluate the safety of anterior cervical disc arthroplasty (CDA) performed in an ambulatory setting in an Eastern European population. All existing studies evaluating safety and efficiency of outpatient CDA have originated from high-volume ASCs from the USA. Methods:We retrospectively reviewed 103 consecutive patients who underwent outpatient CDA between January 2018 and February 2020 in order to assess the safety of outpatient single- and multi-level CDA procedures. Various operative data was collected, including adverse events. Results:One patient required reintervention for reposition of the implant, resulting in a reoperation rate of 0.97%. Of the total 149 levels treated, the risk of readmission per level treated was 0.67%. Other AEs included prolonged postoperative hoarseness (laryngeal nerve dysfunction) in two (1.94%) patients, which for one patient resolved within one year. There were no other cases of reintervention, hospital readmission, or postoperative emergency visits. Conclusion:To our knowledge, this is the first study to evaluate the safety of CDA in the ambulatory setting in an Eastern European population. Our data suggests that CDA may be considered safe in the outpatient setting in appropriately selected patients. The 30-day reintervention rate was 0.97%, while AE rate was 1.94%. The reoperation and AE rates were similar to or lower than the complication rates reported by large US outcome studies.