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1.
Prev Vet Med ; 181: 105060, 2020 Aug.
Article in English | MEDLINE | ID: mdl-32540717

ABSTRACT

Bovine Nodular Thelitis (BNT) is a granulomatous dermatitis of teat skin associated with acid-fast bacilli. A similar condition has been recorded in a dairy goat flock in France recently. The causative agent was shown to be related to the leprosy-causing bacilli Mycobacterium leprae and M. lepromatosis, then sequenced and named M. uberis. Following the initial report in goats, the aim of this study was to investigate new cases of Caprine Nodular Thelitis (CNT) in the same area to confirm the presence of M. uberis by molecular techniques and to get a better description of the clinical signs and of the affected flocks. Twenty-six animals (25 females and 1 male) from 11 flocks were included in the study. Lesions were located on the udder/teat skin (24/25), on the body skin (6/25) or on the scrotum skin (1/1). Udder skin lesions were circular, nodular and/or ulcerate covered with a crust and associated with supramammary lymph node enlargement. Body skin lesions were located at different parts of the body, showed large necrotizing ulcers with undetermined edges and were associated with regional lymph node enlargement. Histopathological results indicated granulomatous dermatitis and lymphadenitis of varying intensity with no acid-fast bacilli seen after Fite-Faraco staining. M. uberis DNA was amplified from 26 samples out of 47 (udder: 11/22; lymph node: 11/20; body: 4/5). The female goats were mostly older than 4 year of age and originated from breeding units characterized by large flock size and high proportion of goat in continuous lactation.


Subject(s)
Goat Diseases/pathology , Mastitis/veterinary , Mycobacterium Infections/veterinary , Mycobacterium/isolation & purification , Animals , Female , Genital Diseases, Male/microbiology , Genital Diseases, Male/pathology , Genital Diseases, Male/veterinary , Goat Diseases/microbiology , Goats , Male , Mastitis/microbiology , Mastitis/pathology , Mycobacterium Infections/microbiology , Mycobacterium Infections/pathology , Scrotum/pathology
2.
Ann Occup Hyg ; 55(2): 152-63, 2011 Mar.
Article in English | MEDLINE | ID: mdl-21177264

ABSTRACT

OBJECTIVES: The association between workplace bullying and psychotropic drug use is not well established. This study was aimed at exploring the association between workplace bullying, and its characteristics, and psychotropic drug use and studying the mediating role of physical and mental health. METHODS: The study population consisted of a random sample of 3132 men and 4562 women of the working population in the south-east of France. Workplace bullying, evaluated using the validated instrument elaborated by Leymann, and psychotropic drug use, as well as covariates, were measured using a self-administered questionnaire. Covariates included age, marital status, presence of children, education, occupation, working hours, night work, physico-chemical exposures at work, self-reported health, and depressive symptoms. Statistical analysis was performed using logistic regression analysis and was carried out separately for men and women. RESULTS: Workplace bullying was strongly associated with psychotropic drug use. Past exposure to bullying increased the risk for this use. The more frequent and the longer the exposure to bullying, the stronger the association with psychotropic drug use. Observing bullying on someone else at the workplace was associated with psychotropic drug use. Adjustment for covariates did not modify the results. Additional adjustment for self-reported health and depressive symptoms reduced the magnitude of the associations, especially for men. CONCLUSIONS: The association between bullying and psychotropic drug use was found to be significant and strong and was partially mediated by physical and mental health.


Subject(s)
Bullying , Health Status , Mental Disorders , Psychotropic Drugs , Substance-Related Disorders/epidemiology , Workplace , Adult , Bullying/psychology , Cross-Sectional Studies , Female , France/epidemiology , Humans , Male , Mental Disorders/epidemiology , Middle Aged , Prevalence , Risk Factors , Substance-Related Disorders/psychology , Surveys and Questionnaires
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