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1.
Neurochirurgie ; 56(4): 344-9, 2010 Aug.
Article in French | MEDLINE | ID: mdl-20097390

ABSTRACT

UNLABELLED: The frequency of intramedullary tumors is 0.5 cases per year for 100,000 inhabitants. The study reported herein was a retrospective study conducted from January 1985 to September 2007. MATERIAL: Seventy-nine cases were distributed in the following manner: ependymomas, 38; astrocytomas, 22; oligodendrogliomas, four; gangliogliomas, two; hemangioblastomas, 10 (nine sporadic cases and one case of Von Hippel-Lindau disease); primitive melanoma, one; and intramedullary neurinomas, two. Three patients were lost to follow-up and 10 patients died. METHOD: All patients were explored using MRI and were operated using a microsurgical technique. Tumor removal was complete in the cases of ependymoma and hemangioblastoma and subtotal in the cases of astrocytoma. RESULTS: Ependymoma: 38 cases with three cases of ependymoblastoma. Mean age: 47 years (range, 17-74 years); 17 males and 21 females. Diagnostic delay: less than one year, 11; one year, 15 cases; two years, nine cases; three years, three cases. Seven recurrences with one 35 years after a prior removal. Localizations: cervical and cervicodorsal, 19; dorsal, ten; dorsolumbar, seven; holomedullary, one. Number of levels concerned: 5-12 (with the cysts associated). Mean follow-up was 10 years (range, two months to 35 years). Patients stabilized, 19; worse, six; improved, nine. Patients deceased: four, one by suicide, three cases of ependymoblastoma (survival, seven months). Astrocytomas: 22 cases, with 14 cases of astrocytoma, two pilocytic astrocytoma, four malignant astrocytoma, and two glioblastoma. Mean age: 44 years (range, 22-73 years); 14 males and eight females. Diagnostic delay: malignant tumors, one to nine months; low grades; three to six years (range, eight months to 25 years). Number of levels concerned: two to eight. Mean follow-up: seven years (range, six months to 10 years). Stabilized patients: 13; worse, five; deaths, four. Oligodendroglioma: four cases. Mean age: 58 years; two males and two females. Diagnostic delay: 10months. Localization: cervical, three; dorsal, one. Oligodendroglioma A, two; B, two. Results: two cases stabilized, one case with recurrence, and one patient deceased. Ganglioglioma: two. Both cases were associated with scoliosis. Recurrence in the eighth month and two years for the second case. One patient died. Hemangioblastoma: 10 cases, nine sporadic and one case of Von Hippel-Lindau disease. Nine cervical localizations, one on the medulla cone. Mean age: 45 years (range, 11-54 years); eight males and two females. Total removal in nine cases. One case of recurrence seven years after a prior surgery and operated a second time with no recurrence after 10 years of follow-up. Intramedullary neurinomas: two cases with a total removal and 15 years of follow-up. Primitive melanoma: one case with mediothoracic location. Treatment with surgery plus radiotherapy. Follow-up, seven years without recurrence. CONCLUSION: Total removal of the intramedullary tumors is a challenge. In cases of removal, the risk of worsening status is 18-19.5%. Subtotal or incomplete removal 27-40% risk of recurrence.


Subject(s)
Brain Stem Neoplasms/surgery , Adolescent , Adult , Aged , Brain Stem Neoplasms/epidemiology , Brain Stem Neoplasms/mortality , Delayed Diagnosis , Female , Follow-Up Studies , France/epidemiology , Humans , Magnetic Resonance Imaging , Male , Microsurgery , Middle Aged , Neoplasm Recurrence, Local , Neurosurgical Procedures , Treatment Outcome , Young Adult
2.
Rev Neurol (Paris) ; 153(3): 212-4, 1997 Apr.
Article in French | MEDLINE | ID: mdl-9296138

ABSTRACT

A 30 year old women, beginning her 19th day postpartum, was admitted for lowering of alertness. The day before she complained of cephalalagia. Neurologic examination showed pyramidal tract signs on the right part of the body, a bilateral Babinski sign, and central oculomotor palsy. She started a treatment by nasal pulverization of phenylephrine, a sympathomimetic vasoconstrictor, one week before, and took bromocriptine (5 mg per day) from childbirth to second week postpartum. CT scan was normal. Lumbar puncture showed a high level of proteins, from transsudative origin. Cerebral angiography showed a beading aspect of arterial branches, especially in the left middle cerebral artery territory. Two days after drug withdrawal, the patient recovered. This angiographic pattern has already been described in cases of cerebral angiopathy due to sympathomimetic drug abuse, and in cases of postpartum cerebral angiopathy. The chronology, in our case, makes the responsibility of the phenylephrine very likely. Nonetheless, ergot derivatives (i.e. ergonovine, bromocriptine) have also been accused of giving cerebral postpartum angiopathy. In our case, we think that bromocriptine may have triggered the cerebral angiopathy due to phenylephrine.


Subject(s)
Cerebral Arterial Diseases/etiology , Puerperal Disorders , Bromocriptine/adverse effects , Cerebral Arterial Diseases/chemically induced , Drug Therapy, Combination , Female , Humans , Iatrogenic Disease , Nasal Decongestants/adverse effects , Phenylephrine/adverse effects , Pregnancy , Risk Factors , Vasoconstrictor Agents/adverse effects
9.
12.
Neurochirurgie ; 26(3): 197-9, 1980.
Article in French | MEDLINE | ID: mdl-7464972

ABSTRACT

On the basis of a series of 255 severe head injuries, the authors present a clinical, radiological and anatomical study of central transtentorial impaction. Anatomical examination reveals the frequency of central impaction which affects from above downwards and in succession all of the axial structures in their median part. Clinically, these lesions fall into three categories in terms of signs: homogeneous and corresponding to the anatomical lesions. Scanner findings confirm the anatomoclinical data and provide important information in the assessment of prognosis.


Subject(s)
Brain Injuries/pathology , Brain/pathology , Brain Injuries/complications , Brain Injuries/diagnostic imaging , Cerebral Angiography , Cerebral Hemorrhage/complications , Humans , Prognosis , Tomography, X-Ray Computed
15.
Chir Pediatr ; 19(2): 107-10, 1978.
Article in French | MEDLINE | ID: mdl-709702

ABSTRACT

This current report of our experience of Cotrel's method falls within the context of continuing the developments in our treatment of scoliosis. Our follow-up for Harrington's operation is 13 years, 281 patients having undergone surgery. On other words, having known the beginnings of this surgery, we are in a position to measure the progress represented by Berckoise's technique (7, 6, 8).


Subject(s)
Kyphosis/surgery , Scoliosis/surgery , Adolescent , Child , Female , Follow-Up Studies , Humans , Male , Methods
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