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1.
Tunis Med ; 88(5): 330-4, 2010 May.
Article in French | MEDLINE | ID: mdl-20517829

ABSTRACT

BACKGROUND: Inhalation of laryngotracheobronchial foreign body in children is a serious accident that may compromise the prognosis of the child and the respiratory function in the long term. AIM: identify the predictive factors of respiratory sequelae of laryngotracheobronchial foreign body inhalation. METHODS: This retrospective study was conducted in the children hospital of Tunis during a period of nine years (2000 - 2008). In all statistical tests, the significance level was set at 0.05. RESULTS: 60 children were included in the study. The average age was 24.9 +/- 3.4 months. 2 / 3 of the children were boys. The foreign body was plant in 80% of cases. The penetration syndrome was reported in 83.7% of cases. The average time of stay of foreign body was 14 days. The chest radiograph was abnormal in 77.4% of cases. Endoscopic extraction was performed in 59 cases and a pneumectomy was conducted in one child. 30 children were followed for an average of 23 months. 18 children had not respiratory sequelae (clinical, radiological and scintigraphic). 10 children had respiratory sequelae (clinical and radiological and/or scintigraphic) at the last follow-up and four patients developed bronchial dilatation. Respiratory sequelae were correlated with the stay period of the foreign body exceeding 84H. Neither age, nor sex, nor the nature of foreign body or its location, nor the presence of radiological opacity at the initial radiograph, were predictive factors of respiratory sequelae. CONCLUSION: The inhalation of foreign body is a serious accident affecting essentially male infants. Clinical, radiological and scintigraphic follow up is mandatory.


Subject(s)
Foreign Bodies/complications , Foreign Bodies/therapy , Bronchoscopy , Child , Child, Preschool , Female , Foreign Bodies/diagnostic imaging , Humans , Infant , Lung/diagnostic imaging , Lung Diseases/etiology , Male , Radiography , Retrospective Studies
3.
J Appl Genet ; 50(3): 289-91, 2009.
Article in English | MEDLINE | ID: mdl-19638686

ABSTRACT

A male infant with partial monosomy 10 q and partial trisomy 11q as a result of de novo unbalanced translocation between the long arms of chromosomes 10 and 11: der(10)t(10;11)(q26;q13) is described. He had craniofacial dysmorphy, congenital heart defects, urogenital and cerebral anomalies, and severe developmental delay. To the best of our knowledge, this is the first report of this combination of chromosomal abnormalities.


Subject(s)
Abnormalities, Multiple/genetics , Chromosomes, Human, Pair 10/genetics , Chromosomes, Human, Pair 11/genetics , Monosomy/genetics , Translocation, Genetic , Trisomy/genetics , Humans , Infant , Karyotyping , Male
4.
Arch Pediatr ; 8(12): 1344-7, 2001 Dec.
Article in French | MEDLINE | ID: mdl-11811031

ABSTRACT

Mediastinal mature teratomas are rare in children. Diagnosis is often made in the presence of a complication. We report a case of a mature mediastinal teratoma, complicated by its opening in the lung. The patient was a four-year-eight-month-old girl. She was admitted for fever, cough and dyspnea. The chest radiography showed a large mediastinal mass with calcifications. The CT scans and MRI aided in establishing the diagnosis. Biological tests (alpha-foetoproteins and beta-HCG) confirmed the benignity of the tumor. The child was operated on with full success.


Subject(s)
Lung Neoplasms/diagnostic imaging , Mediastinal Neoplasms/diagnostic imaging , Teratoma/diagnostic imaging , Child, Preschool , Female , Humans , Lung/pathology , Lung Neoplasms/pathology , Lung Neoplasms/surgery , Mediastinal Neoplasms/pathology , Mediastinal Neoplasms/surgery , Neoplasm Invasiveness , Pneumonectomy , Teratoma/pathology , Teratoma/surgery , Tomography, X-Ray Computed
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