Role of Potassium Ions in Regulation of Calcium-Activated Chloride Channels.

Using the patch-clamp method in the whole cell configuration, it was shown that external potassium ions play an important role in the regulation of calcium-activated chloride channels (CaCCs). A clear dependence of the conductivity of the СаССs on the external potassium concentration was shown. The effect of external potassium in the range 0-15 mM on the conductivity of chloride channels was significantly greater than the effect it had on other ionic currents (sodium or potassium). There is reason to believe that these changes in the conductivity of CaCCs may contribute to the development of pathophysiological processes such as hypokalemia or hyperkalemia.

[Study of the structure of mannans from Candida maltosa and Candida tropicalis using 13C-NMR spectroscopy]. / Izuchenie struktury mannanov drozhzhei Candida maltosa i Candida tropicalis metodom 13C-IaMR spektroskopii.

Mannans were isolated from six Candida strains and characterized. 13C-NMR spectroscopy revealed interspecific and interstrain difference of the yeasts in the structure of their mannans.