[Functional suitability of iodinated casein in the prevention of iodine deficiency]. / Funktsional'naia prigodnost' iodkazeina dlia profilaktiki iodnoi nedostatotochnosti.

At least 1.5 billion in the world and over 100 million Russians live in iodine-deficiency areas. The sequelae of this condition are well known. The paper discusses the properties of the iodinated lactoprotein caseoiodine designed by the MRRC researchers and its capacities and advantages for using in the prevention of iodine deficiency. The assimilation of iodine from caseoiodine corresponds to the body's status: it significantly accumulates more frequently in the thyroid in dietary iodine deficiency (Group 1) and to a lesser degree in adequate dietary iodine intake (Group 2) and, by hour 72, amounts to 36.3 and 31.4% of the ingested amount, respectively (P < 0.05). The findings are in agreement with the data available in the literature on the involvement of hepatic enzymes in regulating the metabolism of iodine during its intake in the protein (casein)-bound form and in increasing its fecal excretion (up to 40% in Group 2) whereas 95% iodine excrete with urine when inorganic iodine is consumed.

[The potential of rose Bengal treatment for photodynamic therapy of tumors]. / Vozmozhnosti primeneniia bengal roz dlia fotodinamicheskoi terapii opukholei.

An experimental treatment with rose bengal showed that optimal effectiveness of photodynamic therapy of sarcoma M-1 was achieved 3-4 hr after intraperitoneal injection of 10 mg/kg body.

[A comprehensive radioisotope assessment of the effectiveness of Ferrum Lek in patients with iron-deficiency anemia]. / Kompleksnaia radioizotopnaia otsenka éffektivnosti preparata Ferrum Lek u bol'nykh zhelezodefitsitnoi anemiei.

Before and after treatment iron metabolism was evaluated in 37 iron deficient women given intravenous Ferrum Lek. In addition to standard blood counts and serum iron tests, iron metabolism was investigated with Fe-59 whole body radiometry in a low-background camera. The treatment effect was assessed in 1.3 and 6 months. The red blood cells and iron content in the serum returned to normal values. The effect persisted for 6 months. The initial 3 months iron accumulated in the depot, being further distributed in the blood. Total body iron 6 months after the treatment was at the baseline levels. It is thought adequate to use Ferrum Lek in the management of women with iron deficiency anemia.