Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
Add more filters










Database
Language
Publication year range
1.
Khirurgiia (Mosk) ; (7): 4-13, 2011.
Article in Russian | MEDLINE | ID: mdl-21983527

ABSTRACT

Treatment results of 5 patients with unformed intestinal fistulae are represented. High unformed intestinal fistulae are acknowledged to be completely unsuitable for conservative treatment and should be operated on. Complex treatment should include complete parenteral feeding, adequate fecal diversion with the use of aspirational drainage. Surgical treatment must be y the increase of fistula discharge or absence of fistula formation. Low intestinal fistulae should better be surgically dissected after their organization, otherwise urgent surgery is to be performed by complications development, such as purulent leakage into the abdominal cavity or severe wound infection.


Subject(s)
Abdominal Cavity/surgery , Digestive System Surgical Procedures/methods , Intestinal Fistula , Intestine, Small/surgery , Intraoperative Care/standards , Surgical Wound Infection/complications , Abdominal Cavity/diagnostic imaging , Abdominal Cavity/pathology , Adult , Aged , Anastomotic Leak/physiopathology , Female , Humans , Intestinal Fistula/diagnosis , Intestinal Fistula/etiology , Intestinal Fistula/physiopathology , Intestinal Fistula/therapy , Intestine, Small/diagnostic imaging , Intestine, Small/pathology , Middle Aged , Parenteral Nutrition , Peritonitis/physiopathology , Professional Practice , Radiography , Severity of Illness Index , Suction/methods , Treatment Outcome , Water-Electrolyte Imbalance/physiopathology
2.
Ter Arkh ; 73(4): 31-3, 2001.
Article in Russian | MEDLINE | ID: mdl-11494443

ABSTRACT

AIM: To evaluate effectiveness of sulodexide in patients with pyonecrotic complications of diabetic foot. MATERIAL AND METHOD: Sulodexide was given to 15 patients which were examined for blood fibrinogen, foot tissues saturation with oxygen, microbic contamination of the wound tissue. In addition, ultrasound dopplerography of foot arteries, laser doppler flowmetry were performed. RESULTS: Fibrinogen in peripheral blood fell, arteriovenous shunting diminished, capillary blood flow and oxygen saturation of the tissues improved. CONCLUSION: Even early sulodexide treatment is effective at different stages of the pathological process in diabetic patients with severe pyonecrotic lesion of the lower limbs as it recovers microcirculatory blood flow.


Subject(s)
Diabetic Foot/drug therapy , Glycosaminoglycans/therapeutic use , Hypoglycemic Agents/therapeutic use , Diabetic Foot/pathology , Diabetic Foot/physiopathology , Glycosaminoglycans/administration & dosage , Humans , Hypoglycemic Agents/administration & dosage , Microcirculation , Necrosis , Suppuration , Time Factors
3.
Khirurgiia (Mosk) ; (10): 44-8, 1999.
Article in Russian | MEDLINE | ID: mdl-10540553

ABSTRACT

For the period from 1996 to 1998 in the Division of wounds and wound infection of A.V. Vishnevsky Institute of Surgery 92 patients with pyonecrotic forms of "diabetic foot" underwent thorough examination and treatment. The patients were divided into groups by the form of "diabetic foot": with pyonecrotic forms of "diabetic foot" without critical ischemia (group 1) and with it (group 2). In 18 patients of both groups the data of electron autoradiography were used to reveal peculiarities of the wound process. Group 1 patients had at admittance a large number of neutrophiles in various stages of destruction in biopsies of the wound. In patients of group 2 a great majority of the vessels in biopsies of the wound were in different stages of destruction with lost connections between their separate cells or some of their part absent. Separate cells (endotheliocytes and pericytes) which make up the walls of destroying vessels, were synthesizing RNA and were functionally active. In both groups, the studied parts of the wound before plastic repair of its defect usually represented as well developed granulation tissues with a number of microvessels and cells. Intensive synthesis of PNA in the cells of microvascular wall evidenced of their high functional activity, and the synthesis of DNA in them showed their ability for proliferation, i.g.--for growth. Thus, microangiopathy was reversible, and the solution of the problem of critical ischemia should be considered in the light of macroangiopathy. Thus, in patients of group 1 the cause of pyonecrotic damage consists in infection process, while in patients of group 2--in combination of infection with ischemia of the extremity. In both groups pyonecrotic disease of the extremity ruses at the background of severe disturbances of cellular immunity.


Subject(s)
Diabetic Foot/surgery , Surgical Procedures, Operative/methods , Diabetic Foot/mortality , Diabetic Foot/pathology , Humans , Necrosis , Retrospective Studies , Suppuration , Surgical Procedures, Operative/mortality , Survival Rate , Treatment Outcome
SELECTION OF CITATIONS
SEARCH DETAIL
...