[THE IMMUNOLOGIC INDICATORS IN PATIENTS WITH CARIES OF CONTACT SURFACES OF LATERAL TEETH].

The samplings of patients aged 18-45 years with caries of contact surfaces of lateral teeth (n=18) and healthy adults aged 18-20 years with intact teeth (n=18) were examined The saliva taken in rotary vial on empty stomach in amount of 3-4 mi served as assay for analysis. To identify secretory immunoglobulin A, interleukin lß, interleukin-4 and interferon y saliva was centrifuged during 15 min under 1500 rpm. The supernatant fluid was analyzed using enzymoimmunoassay (test-systems "Vector-Best", Novosibirsk). The registration of reaction was implemented using multiscan Labsystem under wavelength 450 nm. The content of secretory immunoglobulin A was expressed in mg/l, cytokines - in pg/ml. It is demonstrated that in patients with caries average level of interleukin lß was almost two times higher (p<0.05) than analogous indicator in healthy examined patients. In healthy patients average level of interferon γ significantly (more than in 10 times) exceeded upper limit of allowable standard and was higher (p<0.05) in comparison with such in patients with caries of contact surfaces. The analysis of content of secretory immunoglobulin A in saliva established that in healthy patients average values of the given indicator were higher (p<0.05) than in patients with caries of contact surfaces of lateral teeth. The lower content of secretory immunoglobulin A and interferon y against the background of increased level of interleukin lß was detected in saliva of patients with caries of contact surfaces of lateral teeth. This occurrence can be considered as factor predisposing to development of caries process.

[Theoretical and clinical prerequisites for the use of fragments of molar roots as abutment for dentures]. / Teoreticheskie i klinicheskie predposylki k ispol'zovaniiu fragmentov kornei moliarov v kachestve opory zubnykh protezov.

Experimental and clinical studies confirmed the possibility of using fragments of a multi-root tooth as abutment tooth for a bridge denture. When planning orthodontic treatment, choosing the abutment teeth, designing the denture, and treating the patient the orthodontist should be able to use the information on the maximum allowable loading of the fragments of resected teeth. A positive factor in utilization of the remaining tooth fragment is the ratio of clinical crown and root length, which should be inversely proportional. The study showed that retention of the morphofunctional integrity of dentition is possible when using dentures ensuring the optimum regulation stress (no higher than physiologically tolerable) in abutment tissues. Analysis of remote clinical and X-ray data showed normalization of the periodontal function of tooth fragments after tooth-sparing operations in cases when the patients were fitted with prostheses with consideration for theoretically valid methods for estimation of reserve force.

[Gingivo-dental sparing strategy of orthodontic treatment (fitting with permanent dentures)]. / Taktika zubodesnevogo sokhraneniia pri protezirovanii nes"emnymi zubnymi protezami.

Development of inflammatory process in the marginal part of the mucosa is caused not only by epithelial injury during tooth preparation and dental plaque accumulation, but by irregular contour and position of the artificial crown edge as well. Clinical, x-ray, and cytoenzymological studies showed that orthodontic treatment with cermet and polyceramic dentures with fixation of the supporting elements at the level of the gingival edge in tissues adjacent to the tooth causes the slightest pathological changes. The compensatory adaptive processes in this area of the buccal mucosa are the most pronounced if preparation of hard dental tissues is combined with closed currettage of periodontal pouches, which was confirmed by remote clinical results and laboratory findings in patients with slight and medium-severe periodontitis.