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1.
Pan Afr Med J ; 47: 92, 2024.
Article in English | MEDLINE | ID: mdl-38799189

ABSTRACT

Indoxacarb, a large-spectrum non-organophosphorus oxadiazine insecticide, is broadly used in farming whose mechanism of action is the blockage of voltage-gated sodium channels of insects. There is restricted data on human poisoning. We report a case of an 18-year-old male patient without comorbidities presented with unconsciousness and cyanosis after the intentional ingestion of indoxacarb in a suicide attempt. Methemoglobinemia was clinically suspected and was successfully treated after methylene blue injection, associated with supportive and symptomatic management. This case emphasizes the importance of considering methemoglobinemia after indoxacarb ingestion in addition to its early recognition and timely injection of methylene blue which led to complete recovery without sequelae.


Subject(s)
Insecticides , Methemoglobinemia , Methylene Blue , Oxazines , Suicide, Attempted , Humans , Methemoglobinemia/chemically induced , Methemoglobinemia/diagnosis , Male , Methylene Blue/administration & dosage , Adolescent , Insecticides/poisoning , Oxazines/poisoning , Oxazines/administration & dosage , Cyanosis/chemically induced
2.
Pan Afr Med J ; 42: 295, 2022.
Article in English | MEDLINE | ID: mdl-36415340

ABSTRACT

Scleroderma is an autoimmune connective tissue disorder which is characterized by fibrosis of visceral organs, blood vessels and skin. The most common manifestations of lung disease in systemic sclerosis are interstitial lung disease and pulmonary hypertension and, together, are the leading cause of mortality in systemic sclerosis. Recently, we notice a new pattern called Combined-pulmonary emphysema and lung fibrosis. Most patients with this entity are male smokers or ex-smokers. This entity is characterized by the coexistence of both centro-lobular and para-septal emphysema in the upper lobes and interstitial lung disease in the lower lobes. Here, we present a case of a nonsmoker adult woman with systemic sclerosis, in which High Resolution Computed Tomography of lung showed combined fibrosis and emphysema with atypical radiological presentation and unusual distribution. This case outlines the importance of recognizing the presence of combined fibrosis and emphysema in patient with systemic sclerosis even without smoking history.


Subject(s)
Emphysema , Lung Diseases, Interstitial , Pulmonary Emphysema , Scleroderma, Localized , Scleroderma, Systemic , Adult , Female , Humans , Male , Pulmonary Emphysema/diagnostic imaging , Pulmonary Emphysema/etiology , Smokers , Scleroderma, Systemic/complications , Lung Diseases, Interstitial/diagnostic imaging , Lung Diseases, Interstitial/etiology , Fibrosis
3.
Pan Afr Med J ; 38: 274, 2021.
Article in English | MEDLINE | ID: mdl-34122701

ABSTRACT

Spontaneous hemopneumothorax is a rare encountered entity in clinical practice. It can be life threatening, so a prompt diagnosis and therapeutic intervention are required. We report a case of a right spontaneous hemopneumothorax in a 31-year-old man, complicated with hemorrhagic shock. Conservative therapy with only thoracic drainage with close monitoring of outflow and hemodynamic parameters was performed. In front of hemodynamic instability, an emergency video-assisted thoracoscopic surgery was performed. An apical bulla adhering to the parietal pleura has been identified as the source of the bleeding. The resection of the bullae and electrocauterization of the bleeding adhesion were effectuated. The hemostasis was easily achieved. The actual experience suggests that video-assisted thoracoscopic surgery should be performed as soon as possible after the diagnosis of spontaneous hemopneumothorax. Indeed, conservative therapy with chest drainage should only be performed as bridge to recovery for the stabilization before the video-assisted thoracoscopic surgery.


Subject(s)
Hemopneumothorax/therapy , Shock, Hemorrhagic/therapy , Thoracic Surgery, Video-Assisted/methods , Adult , Drainage/methods , Electrocoagulation/methods , Hemopneumothorax/diagnosis , Humans , Male , Shock, Hemorrhagic/diagnosis , Tunisia
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