Subject(s)
Respiratory Tract Infections/etiology , Virus Diseases/etiology , Adolescent , Adult , Aged , Diagnosis, Differential , Female , Humans , Male , Middle Aged , Respiratory Tract Infections/diagnosis , Respiratory Tract Infections/drug therapy , Virus Diseases/diagnosis , Virus Diseases/drug therapyABSTRACT
Enteroviruses--4 polio, 30 Coxsackie and 20 echovirus strains--were isolated from 54 patients with neurologic disease. In 29 cases (53.7%) viruses were isolated from the CSF, blood clot and nerve tissue homogenates. The correlation of the complex clinical data and the localisation of the lesions in the CNS demonstrate the involvement of cranial nerves, of the long bulbar motor pyramidal and extra-pyramidal tracts, of the reticular formation, a.o. These aspects are in accordance with the localisation of the lesions especially in the brain stem and in the hypothalamus, in most of our patients. The extent and complexity of the lesions suggest a predominatly vascular dissemination.
Subject(s)
Central Nervous System Diseases/etiology , Enterovirus Infections , Adult , Coxsackievirus Infections/complications , Cranial Nerves , Echovirus Infections/complications , Enterovirus Infections/complications , Enterovirus Infections/diagnosis , Facial Paralysis/etiology , Humans , Mental Disorders/etiology , Movement Disorders/etiology , Peripheral Nervous System Diseases/etiology , Poliomyelitis/complicationsABSTRACT
From 1961 to 1973 416 Coxsackie viruses were isolated, most of the isolations (303) being done in the last 5 years. Most of the isolates belong to a group A, with a predominance of types A6 and A8. Many variations were observed in strains belonging to the same type, as concerns their isolation in human embryo cell cultures and suckling mice; many Coxsackie A5, A6 and A8 strains showed a low pathogenicity for these animals.
