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1.
J Clin Med ; 13(11)2024 May 29.
Article in English | MEDLINE | ID: mdl-38892908

ABSTRACT

Objectives: Little is known about the post-operative functional outcomes of severely frail femur fracture patients, with previous studies focusing on complications and mortality. This study investigated patient- or proxy-reported outcomes after femur fracture surgery in older adult patients with severe frailty. Methods: This was a retrospective cross-sectional study of older adult (>70 years) patients with severe frailty (defined by a Comprehensive Geriatric Assessment-based Frailty Index (FI-CGA) ≥ 0.40), who underwent femur fracture surgery at a Level 1 Trauma Center. Patients or their proxy (i.e., close relative) reported mobility, psychosocial, and functional outcomes at least 1-year after surgery. Results: Thirty-seven predominantly female (76%) patients with a median age of 85 years (IQR 79-92), and a median FI-CGA of 0.48 (IQR 0.43-0.54) were included. Eleven patients (30%) regained pre-fracture levels of ambulation, with twenty-six patients (70%) able to walk with or without assistance. The majority of patients (76%) were able to have meaningful conversations. Of the patients, 54% of them experienced no to minimal pain, while 8% still experienced a lot of pain. Functional independence varied, as follows: five patients (14%) could bathe themselves; nine patients (25%) could dress themselves; fourteen patients (39%) could toilet independently; and seventeen patients (47%) transferred out of a (wheel)chair independently. Conclusions: Despite the high risk of mortality and perioperative complications, many of the most severely frail patients with surgically treated femur fractures regain the ability to ambulate and live with a moderate degree of independence. This information can help healthcare providers to better inform these patients and their families of the role of surgical treatment during goals of care discussions.

2.
J Orthop Trauma ; 38(3): 148-154, 2024 Mar 01.
Article in English | MEDLINE | ID: mdl-38385974

ABSTRACT

OBJECTIVES: To compare outcomes in patients on direct oral anticoagulants (DOACs) treated within 48 hours of last preoperative dose with those with surgical delays >48 hours. DESIGN: Retrospective cohort study. SETTING: Three academic Level 1 trauma centers. PATIENT SELECTION CRITERIA: Patients 65 years of age or older on DOACs before hip fracture treated between 2010 and 2018. Patients were excluded if last DOAC dose was >24 hours before admission, patient suffered from polytrauma, and/or delay to surgery was not attributed to DOAC. OUTCOME MEASURES AND COMPARISONS: Primary outcome measures were the postoperative complication rate as determined by diagnosis of deep venous thrombosis or pulmonary embolus, wound breakdown, drainage, or infection. Secondary outcomes included transfusion requirement, perioperative bleeding, length of stay, reoperation rates, readmission rates, and mortality. RESULTS: Two hundred five patients were included in this study, with a mean cohort age of 81.9 years (65-100 years), 64% were (132/205) female, and a mean Charlson Comorbidity Index of 6.4 (2-20). No significant difference was observed among age, sex, Charlson Comorbidity Index, or fracture pattern between cohorts (P > 0.05 for all comparisons). Seventy-one patients had surgery <48 hours after final preoperative DOAC dose; 134 patients had surgery >48 hours after. No significant difference in complication rate between the 2 cohorts was observed (P = 0.30). Patients with delayed surgical management were more likely to require transfusion (OR 2.39, 95% CI, 1.05-5.44; P = 0.04). Patients with early surgical management had significantly shorter lengths of stay (5.9 vs. 7.6 days, P < 0.005). There was no difference in estimated blood loss, anemia, reoperations, readmissions, 90-day mortality, or 1-year mortality (P > 0.05 for all comparisons). CONCLUSIONS: Geriatric patients with hip fracture who underwent surgical management within 48 hours of their last preoperative DOAC dose required less transfusions and had decreased length of stay, with comparable mortality and complication rates with patients with surgery delayed beyond 48 hours. Providers should consider early intervention in this population rather than adherence to elective procedure guidelines. LEVEL OF EVIDENCE: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.


Subject(s)
Hip Fractures , Humans , Female , Aged , Aged, 80 and over , Retrospective Studies , Hip Fractures/complications , Hip Fractures/surgery , Reoperation , Drainage , Anticoagulants/therapeutic use
3.
J Bone Joint Surg Am ; 105(17): 1388-1392, 2023 09 06.
Article in English | MEDLINE | ID: mdl-37437021

ABSTRACT

ABSTRACT: ➢ Natural language processing with large language models is a subdivision of artificial intelligence (AI) that extracts meaning from text with use of linguistic rules, statistics, and machine learning to generate appropriate text responses. Its utilization in medicine and in the field of orthopaedic surgery is rapidly growing.➢ Large language models can be utilized in generating scientific manuscript texts of a publishable quality; however, they suffer from AI hallucinations, in which untruths or half-truths are stated with misleading confidence. Their use raises considerable concerns regarding the potential for research misconduct and for hallucinations to insert misinformation into the clinical literature.➢ Current editorial processes are insufficient for identifying the involvement of large language models in manuscripts. Academic publishing must adapt to encourage safe use of these tools by establishing clear guidelines for their use, which should be adopted across the orthopaedic literature, and by implementing additional steps in the editorial screening process to identify the use of these tools in submitted manuscripts.


Subject(s)
Orthopedic Procedures , Orthopedics , Humans , Artificial Intelligence , Publishing , Writing
4.
J Shoulder Elbow Surg ; 28(5): 819-827, 2019 May.
Article in English | MEDLINE | ID: mdl-30928396

ABSTRACT

BACKGROUND: Arthroscopic rotator cuff repair (ARCR) provides excellent clinical outcomes but is often associated with significant postoperative pain. The use of intraoperative anesthesia in conjunction with multimodal pharmacologic strategies is a widely accepted approach for managing surgical pain and reducing opiate use. The purpose of this study was to determine whether using a combined field and suprascapular nerve block with liposomal bupivacaine (LB) in addition to an interscalene block would provide greater pain relief and a reduction in opiate consumption compared with an interscalene block alone. METHODS: The study enrolled 50 patients with full-thickness rotator cuff tears undergoing primary ARCR surgery. Patients were randomized to receive intraoperative LB (n = 25) or not (n = 25) and given postoperative "pain journals" to document visual analog scale pain scores and to track their daily opioid consumption during the first 5 postoperative days. RESULTS: Patients in the LB group reported statistically and clinically lower pain scores during postoperative days 1 and 2 (P < .0001 and P = .03, respectively). In addition, patients in the LB group consumed significantly fewer narcotics than the control group during the 5-day period, demonstrating a 64% reduction in total narcotic consumption (P = .002). CONCLUSION: The findings of this study suggest that the addition of LB to multimodal anesthetic protocols significantly reduces the acute perioperative pain experienced following rotator cuff repair and the number of narcotic pills consumed in the first 5 days after ARCR. Furthermore, the findings provide guidelines for postoperative narcotic prescribing to reduce the quantity of opiates prescribed.


Subject(s)
Analgesics, Opioid/administration & dosage , Anesthetics, Local/administration & dosage , Arthroplasty/adverse effects , Bupivacaine/administration & dosage , Pain, Postoperative/drug therapy , Rotator Cuff Injuries/surgery , Arthroplasty/methods , Arthroscopy/adverse effects , Arthroscopy/methods , Female , Humans , Injections, Intra-Articular , Liposomes , Male , Middle Aged , Nerve Block/methods , Opiate Alkaloids/administration & dosage , Pain Management , Pain Measurement , Pain, Postoperative/diagnosis , Pain, Postoperative/etiology , Rotator Cuff/surgery , Single-Blind Method
5.
Clin Sports Med ; 37(4): 569-583, 2018 Oct.
Article in English | MEDLINE | ID: mdl-30201171

ABSTRACT

A well-designed and sensibly progressed rehabilitation program is vital to successful shoulder arthroplasty outcomes. This article describes the protocol suggested by ONS clinicians to treat the growing young, active patient population undergoing anatomic shoulder arthroplasty. This protocol includes an immediate postoperative phase, early strengthening phase, resistance strengthening and proprioception phase, and advanced sport-specific and goal-specific strengthening and proprioception phase. These patients may progress more quickly than older patients and require more challenging exercises aimed at regaining strength and mobility for activity, thus this protocol emphasizes incorporating full-body training to prevent undue stress on the repair on return to activity.


Subject(s)
Arthroplasty/rehabilitation , Postoperative Care , Shoulder Joint/surgery , Humans , Pain Management , Range of Motion, Articular , Recovery of Function , Shoulder Joint/physiopathology
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