ABSTRACT
Listeriosis is a not uncommon infection in humans, usually associated with immunodeficient states and with newborns. However, relatively few cases have been reported in HIV-infected patients. This scarcity of reported cases has aroused interest in the association of listeriosis and AIDS. In this paper we present a case of meningitis and septicemia caused by Listeria monocytogenes in a female patient with AIDS. A review of recent medical literature indicates that association of listeriosis and AIDS may be more common than it seems. Recent research in host-parasite interaction in listerial infection suggests an important role for tumor necrosis factor (TNF) and for integralin, a bacterial protein, in modulating listerial disease in AIDS patients. Inadequate diagnosis may be in part responsible for the scarcity of reports.
Subject(s)
AIDS-Related Opportunistic Infections/diagnosis , HIV-1 , Meningitis, Listeria/diagnosis , Sepsis/diagnosis , AIDS-Related Opportunistic Infections/drug therapy , Adult , Ampicillin/administration & dosage , Diagnosis, Differential , Female , Humans , Meningitis, Listeria/drug therapy , Sepsis/drug therapy , Substance Abuse, Intravenous/complicationsABSTRACT
Sao relatados quatro casos de estrongiloidiase macica em pacientes sem diagnostico previo da doenca ou tratamento imunossupressor. A doenca, na maioria dos casos, teve um curso cronico, associada a uma sindrome de ma absorcao. Em um caso a sintomatologia que motivou a internacao foi a de uma meningite purulenta que se repetia pela quarta vez. Nao se sabe ao certo qual o desencadeante de tal situacao nos quatro casos apresentados, porem, discute-se o possivel papel do sistema imunologico na defesa contra a invasao pelo S. stercoralis
