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J Anim Sci ; 75(4): 1100-11, 1997 Apr.
Article in English | MEDLINE | ID: mdl-9110226

ABSTRACT

Growth and digestion studies were conducted to evaluate the use of ardacin as a feedgrade antibiotic for enhancing digestive function and growth in grazing steers. In Exp. 1, 90 yearling steers (average initial BW of 248 kg) used in a randomized complete block design (block = weight group) grazed fescue pasture without supplementation (CON) or with daily supplements (DM basis) of .4% of BW supplemental ground corn (CRN) or .4% of BW supplemental corn supplying 120 mg of ardacin (ARD). In Exp. 2, 12 ruminally and duodenally cannulated steers and three ruminally cannulated steers (Hereford x Angus; average BW of 347 kg) were used to evaluate the effects of the same supplements used in Exp. 1 on ruminal fermentation and digestion. In Exp. 1, ARD-supplemented steers weighed more (P < .01) at the conclusion of the study than CRN steers, which together weighed more (P < .01) than CON steers. Average daily gain was greater (P < .10) in supplemented than in CON steers; ARD steers had greater (P < .01) ADG than CRN steers. In Exp. 2, forage intake and harvesting efficiency did not vary (P > .10) with supplementation or type of supplement, but total intake reflected (P = .03) the addition of corn to the forage diet. Addition of ardacin increased (P = .02) ruminal pH compared with CRN steers. Ardacin decreased ruminal molar proportions of acetate and increased (P = .01) propionate proportions when compared with CRN steers. Total tract N digestibility was affected (P < .10) by supplementation and by addition of ardacin to the diet. Addition of ardacin to the ground corn supplement increased ADG, in part by enhancing acetate:propionate ratios and increasing N digestion.


Subject(s)
Aminoglycosides , Anti-Bacterial Agents/pharmacology , Blood Glucose/metabolism , Body Weight/drug effects , Cattle/metabolism , Cattle/physiology , Dietary Fiber/metabolism , Digestion/drug effects , Eating/drug effects , Growth Hormone/blood , Insulin/blood , Nitrogen/metabolism , Rumen/drug effects , Thyroid Hormones/blood , Weight Gain/drug effects , Animals , Anti-Bacterial Agents/administration & dosage , Blood Urea Nitrogen , Body Weight/physiology , Cattle/blood , Diet/veterinary , Digestion/physiology , Eating/physiology , Fermentation/drug effects , Fermentation/physiology , Food, Fortified , Hydrogen-Ion Concentration , Insulin-Like Growth Factor I/analysis , Insulin-Like Growth Factor I/metabolism , Male , Rats , Rumen/physiology , Time Factors , Weight Gain/physiology , Zea mays/standards
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