[Amniotic membrane transplantation in palliative treatment of bullous keratopathy]. / Acoperirea cu membrana amniotica in tratamentul paliativ al keratopatiei edematoase.

PURPOSE: To assess the efficacy of amniotic membrane transplantation for the improvement of symptoms in bullous keratopathy. MATERIAL AND METHOD: Prospective study. 14 patients were operated between 01.02.2003 - 01.02.2006. the follow-up period: between 6 and 42 months with an average of 18 months. The following parameters were evaluated: corneal re-epithelialisation appearance of epithelial bullae, pain, photophobia. RESULTS: In 11 cases there was an improvement of the symptomatology: complete in 8 cases and partial in 3 cases. CONCLUSIONS: Amniotic membrane transplantation is an efficient palliative treatment for bullous keratopathy.

[Genetic aspects of retinoblastoma]. / Aspecte genetice în retinoblastom.

Retinoblastoma is a genetic expression model of the tumors' suppressor genes. This study explains the most important elements of the genetic mechanisms which govern retinoblastoma's appearance and remission. It also attempts to address questions about the risk of patient's relatives getting retinoblastoma.

[Ocular manifestation in amiodarone toxicity--case report]. / Manifestari oculare ale toxicitatii amiodaronei--caz clinic.

The authors present the case of a patient having both toxic keratopathy and maculopathy after a medication with amiodarone. Some of the ocular damages are irreversible, even while amiodarone medication is stopped, which recommends the screening as an efficient tracking method for ocular reversible injuries, avoiding major loss of visual function.

[Cataract surgery in an eye with intraocular tumor]. / Consecintele efectuarii operatiei de cataracta pe un ochi cu tumora intraoculara--caz clinic.

This case present the consequences of performing the cataract surgery on an eye with intraocular tumor, pointing the importance of a detailed and complete examination, even for the benign and easy to diagnostic diseases.

[Histopathological assessment of corneal preservation]. / Evaluarea histopatologica a posibilitatilor de conservare a corneei.

PURPOSE: To show corneal changes after corneal preservation. MATERIAL AND METHOD: There was studied 10 pig corneas: a fresh cornea; two corneas stored in wet chamber at 4 degrees C, 24 and 48 hours; seven corneas stored in Inosol at 31 degrees C, 24 hours, 7, 10, 14, 18, 20 and 22 days. RESULTS: We obtained images of every cornea; we followed epithelial, stromal and endothelial changes. CONCLUSIONS: 1. During corneal preservation there are progressive histological changes, early in epithelium and stroma, later at endothelial level. 2. The safe preservation period in wet chamber at 4 degrees C is 24 hours; the changes found after 48 hours are irreversibile. 3. The safe preservation period in Inosol at 31 degrees C is 14 days.

[Corneal preservation at 31 degrees C--experimental study]. / Conservarea corneei la 31 degrees C--studiu experimental.

PURPOSE: To study the cornea, specially the corneal endothelium in preservation media for different periods of time, trying to assess the best period of preservation. To evaluate the endothelial cell loss during preservation, trying to assess the endothelial cell minimum density for a cornea able to be preserved. MATERIAL AND METHODS: We studied 7 human corneas and 15 pig corneas. We used the inverted specular microscope, Axiovert 100. We used the soft KS 400 for image processing. We used to preservation medium: Inosol-like. We made an initial examination, then after 1,4,7,10 and 14 days. RESULTS: In human corneas the mean cell loss(%) was 4.1% from initial cell density after 4 days of preservation, 14.7% after 7 days, 18.6% after 10 days and 23.4% after 14 days. In pig corneas the mean cell loss (%) was 2.3% from initial cell density after 4 days of preservation, 8.8% after 7 days, 14.9% after 10 days and 23% after 14 days. CONCLUSIONS: The best period of preservation in Inosol-like medium is 7-10 days. This period may be extended to 14 days. During preservation there is an endothelial cell loss which after 14 days is about 23% from initial endothelial cell density (about 550 cell/mm2). The minimum initial endothelial cell density for a cornea to be able to be preserved is 2400 cell/mm2.

[Interpretation of visual field with Humphrey Zeiss Analyser]. / Interpretarea perimetriei computerizate realizata cu perimetrul Humphrey Zeiss.

In the beginning of the article where are defined the notions of the soft of automated perimetry: threshold, kind of tests, the strategy of automated perimetry. Then are shown the steps of automated perimetry interpretation: kind of test and strategy, evaluation of patient reliability, interpretation of the visual field defects (artifacts or no) and statistical analysis.

[Corneal preservation at 4 degrees C--experimental study]. / Conservarea corneei la 4 degrees C studiu experimental.

AIM OF STUDY: To evaluate the 4 degrees C method of corneal preservation (in moist chamber or in preservation media To determine the duration of prevention. MATERIAL AND METHOD: Preservation in moist chamber at 4 degrees C, group of 10 pig eyes. Preservation: the entire globe at 4 degrees C examination: direct specular microscopy with a Tomey device, daily, for 4 days. Preservation in Likorol DX at 4 degrees C, group: 20 pig eyes Preservation: Likorol DX medium, we change the medium after 7 days. examinations: inverse specular microscopy, with a Zeiss device, after 1, 4, 7, 10 and 14 days. RESULTS: Preservation in moist chamber at 4 degrees C. The average endothelial cell loss was 13.2% after a day of preservation and 27.1% after 2 days. Preservation in Likorol DX at 4 degrees C The average endothelial cell loss was 2.8% after a day of preservation, 13.8% after 7 days and 22.6% after 10 days. CONCLUSIONS: The corneal preservation in moist chamber at 4 degrees C is a useful method; it is safe to preserve the globe only for 24 hours. It is safe to preserve corneas in Likorol DX medium for 7 days, there is an endothelial cell loss, about 13.8%.

[Blue-yellow full threshold automated perimetry in glaucoma diagnosis]. / Importanta diagnostica în glaucom a perimetriei computerizate Full Threshold Albastru-Galben.

PURPOSE: To compare White & White and Blue-Yellow Full Threshold automated perimetry. MATERIAL AND METHOD: Group of 37 patients; we used a Humphrey Zeiss automated perimeter. RESULTS: We obtained 49% abnormal white & white visual fields and 62% abnormal blue yellow fields. CONCLUSIONS: Blue Yellow perimetry has higher sensibility than white & white perimetry. We can detect earlier with this test the glaucoma defects.

[Post-inflammatory glaucoma--methods of treatment]. / Glaucomul postinflamator--particularitati de tratament pornind de la un caz clinic.

We show the mechanisms of postinflammatory secondary glaucoma and the possibilities of treatment of this, all of this concerning to an individual case. We evaluate the benefits and risks for every kind of therapeutical approach and we show our choice.

[The loss of endothelial cells after perforating keratoplasty--clinical study]. / Pierderea de celule endoteliale dupa keratoplastia perforanta--studiu clinic.

PURPOSE OF THE STUDY: To determine endothelial cell loss rate after penetrating keratoplasty. To determine for low long this rate remain high. MATERIAL AND METHOD: We have three groups of patients. First group consists of 15 patients without ophthalmic pathology. The second group consists of 15 patients, after cataract surgery. The Third group consists of 20 patients after penetrating keratoplasty, 10 of them with edematous keratoplasty and 10 with keratoconus or central leucoma. Every patient was examined with direct specular microscopy, after 1, 3, 6, 9, 12, 15 and 18 months. RESULTS: In the first group we can't determine an endothelial cell loss. In the second group the endothelial cell loss was 4% per month, 5.9% per month, then the value become normal. In the third endothelial cell was continuous within all intervals. CONCLUSIONS: After penetrating keratoplasty there is a significant endothelial cell loss that continues over 18 month.