1.
J Antibiot (Tokyo)
; 34(10): 1311-7, 1981 Oct.
Article
in English
| MEDLINE
| ID: mdl-7309625
ABSTRACT
A group of novel 4-substituted phenylacetic acids were prepared and coupled with several 7-amino-delta-3-cephems to afford a family of parenterally active cephalosporins. A compound designated 13I had the broadest spectrum of activity and the highest potency of the group against both Gram-positive and Gram-negative bacteria. The activity of 13I included high potency against penicillinase-producing staphylococci and activity against anaerobes, including Bacteroides fragilis.