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Sci Rep ; 9(1): 19000, 2019 12 12.
Article in English | MEDLINE | ID: mdl-31831864

ABSTRACT

We propose a model to generate electrocardiogram signals based on a discretized reaction-diffusion system to produce a set of three nonlinear oscillators that simulate the main pacemakers in the heart. The model reproduces electrocardiograms from healthy hearts and from patients suffering various well-known rhythm disorders. In particular, it is shown that under ventricular fibrillation, the electrocardiogram signal is chaotic and the transition from sinus rhythm to chaos is consistent with the Ruelle-Takens-Newhouse route to chaos, as experimental studies indicate. The proposed model constitutes a useful tool for research, medical education, and clinical testing purposes. An electronic device based on the model was built for these purposes.


Subject(s)
Electrocardiography , Models, Cardiovascular , Signal Processing, Computer-Assisted , Arrhythmias, Cardiac/diagnostic imaging , Computer Simulation , Diffusion , Nonlinear Dynamics , Numerical Analysis, Computer-Assisted , Time Factors , Ventricular Fibrillation/diagnostic imaging
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