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1.
Phys Rev Lett ; 126(2): 023601, 2021 Jan 15.
Article in English | MEDLINE | ID: mdl-33512183

ABSTRACT

Targeting at the realization of scalable photonic quantum technologies, the generation of many photons, their propagation in large optical networks, and a subsequent detection and analysis of sophisticated quantum correlations are essential for the understanding of macroscopic quantum systems. In this experimental contribution, we explore the joint operation of all mentioned ingredients. We benchmark our time-multiplexing framework that includes a high-performance source of multiphoton states and a large multiplexing network, together with unique detectors with high photon-number resolution, readily available for distributing quantum light and measuring complex quantum correlations. Using an adaptive approach that employs flexible time bins, rather than static ones, we successfully verify high-order nonclassical correlations of many photons distributed over many modes. By exploiting the symmetry of our system and using powerful analysis tools, we can analyze correlations that would be inaccessible by classical means otherwise. In particular, we produce on the order of ten photons and distribute them over 64 modes. Nonclassicality is verified with correlation functions up to the 128th order and statistical significances of up to 20 standard deviations.

2.
Phys Rev Lett ; 123(21): 213604, 2019 Nov 22.
Article in English | MEDLINE | ID: mdl-31809170

ABSTRACT

We introduce a filter using a noise-free quantum buffer with large optical bandwidth that can both filter temporal-spectral modes as well as interconvert them and change their frequency. We theoretically show that such quantum buffers optimally filter out temporal-spectral noise, producing identical single photons from many distinguishable noisy single-photon sources with the minimum required reduction in brightness. We then experimentally demonstrate a noise-free quantum buffer in a warm atomic system that is well matched to quantum dots. Based on these experiments, simulations show that our buffer can outperform all intensity (incoherent) filtering schemes for increasing indistinguishability.

3.
Phys Rev Lett ; 122(5): 053602, 2019 Feb 08.
Article in English | MEDLINE | ID: mdl-30822007

ABSTRACT

We report on the first experimental reconstruction of an entanglement quasiprobability. In contrast to related techniques, the negativities in our distributions are a necessary and sufficient identifier of separability and entanglement and enable a full characterization of the quantum state. A reconstruction algorithm is developed, a polarization Bell state is prepared, and its entanglement is certified based on the reconstructed entanglement quasiprobabilities, with a high significance and without correcting for imperfections.

4.
Philos Trans A Math Phys Eng Sci ; 375(2099)2017 08 06.
Article in English | MEDLINE | ID: mdl-28652496

ABSTRACT

In the last few decades, there has been much progress on low loss waveguides, very efficient photon-number detectors and nonlinear processes. Engineered sum-frequency conversion is now at a stage where it allows operation on arbitrary temporal broadband modes, thus making the spectral degree of freedom accessible for information coding. Hereby the information is often encoded into the temporal modes of a single photon. Here, we analyse the prospect of using multi-photon states or squeezed states in different temporal modes based on integrated optics devices. We describe an analogy between mode-selective sum-frequency conversion and a network of spatial beam splitters. Furthermore, we analyse the limits on the achievable squeezing in waveguides with current technology and the loss limits in the conversion process.This article is part of the themed issue 'Quantum technology for the 21st century'.

5.
Phys Rev Lett ; 115(2): 023601, 2015 Jul 10.
Article in English | MEDLINE | ID: mdl-26207467

ABSTRACT

We report on the implementation of a time-multiplexed click detection scheme to probe quantum correlations between different spatial optical modes. We demonstrate that such measurement setups can uncover nonclassical correlations in multimode light fields even if the single mode reductions are purely classical. The nonclassical character of correlated photon pairs, generated by a parametric down-conversion, is immediately measurable employing the theory of click counting instead of low-intensity approximations with photoelectric detection models. The analysis is based on second- and higher-order moments, which are directly retrieved from the measured click statistics, for relatively high mean photon numbers. No data postprocessing is required to demonstrate the effects of interest with high significance, despite low efficiencies and experimental imperfections. Our approach shows that such novel detection schemes are a reliable and robust way to characterize quantum-correlated light fields for practical applications in quantum communications.

6.
Exp Cell Res ; 225(1): 67-74, 1996 May 25.
Article in English | MEDLINE | ID: mdl-8635518

ABSTRACT

The 20S proteasome is widely viewed at as a cytoplasmic multicatalytic proteinase complex: immunocytochemical investigations, however, show that proteasomes are localized in the cytoplasm as well as in the nucleus within the same cell. Strong nuclear accumulation of proteasomes is observed in rapidly dividing cells such as in the early stages of Drosophila embryogenesis and in tumorigenic cells. In fact, dependent on the metabolic state of a certain tissue or cell type its cellular distribution appears differentially regulated. Several of the proteasomal alpha-type subunits carry putative nuclear localization signals which may or may not take part in the regulation of the intracellular distribution of 20S proteasomes. We have examined the functional role of the putative nuclear localization signal (NLS) -KKKQKK-in the Drosophila PROS-28.1 subunit by deletion mutagenesis and transfection experiments. Linkage of the putative PROS-28.1 NLS to BSA as reporter protein and in vitro import studies with permeabilized mouse NIH 3T3 cells show that this NLS is able to induce complete translocation of the reporter protein into the cell nucleus. For analysis of the NLS within the 28-kDa subunit, cDNA deletion constructs were cloned into a pSG5 expression vector and transiently transfected into mouse fibroblast cells. Whereas the deletion of the NLS alone resulted only in a slight impairment of subunit transport into the nucleus, removal of the C-terminal 96 amino acid residues abolished nuclear translocation completely.


Subject(s)
Cell Nucleus/metabolism , Cysteine Endopeptidases/metabolism , Multienzyme Complexes/metabolism , Protein Sorting Signals/metabolism , 3T3 Cells , Amino Acid Sequence , Animals , Antibodies/immunology , Antibody Specificity , Cysteine Endopeptidases/immunology , Drosophila , Eukaryotic Cells , Mice , Molecular Sequence Data , Multienzyme Complexes/immunology , Proteasome Endopeptidase Complex , Protein Sorting Signals/immunology , Rabbits , Serum Albumin, Bovine/metabolism
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