1.
Bone Marrow Transplant
; 54(12): 1923-1925, 2019 12.
Article
in English
| MEDLINE
| ID: mdl-30890768
Subject(s)
Antineoplastic Agents, Alkylating/adverse effects , Bendamustine Hydrochloride/adverse effects , Kidney/drug effects , Lymphoma/drug therapy , Multiple Myeloma/drug therapy , Antineoplastic Agents, Alkylating/pharmacology , Antineoplastic Agents, Alkylating/therapeutic use , Bendamustine Hydrochloride/pharmacology , Bendamustine Hydrochloride/therapeutic use , Female , Humans , Incidence , Male
2.
A A Pract
; 12(4): 96-98, 2019 Feb 15.
Article
in English
| MEDLINE
| ID: mdl-30052534
ABSTRACT
We present a case of a 73-year-old cancer patient with low transcutaneous oxygen saturation who was transferred to the intensive care unit after deployment of the rapid response team. Differential diagnosis remained broad until methemoglobinemia (MetHb) was detected.MetHb was induced by administration of rasburicase, which was given to prevent tumor lysis syndrome. In a follow-up examination, glucose-6-phosphate dehydrogenase deficiency was found to be the cause of MetHb after rasburicase exposure.Diagnosis was made by either measuring arterial MetHb or CO oximeter. Treatment options involve transfusion and methylene blue, if glucose-6-phosphate dehydrogenase deficiency is not present.