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1.
Gait Posture ; 76: 198-203, 2020 02.
Article in English | MEDLINE | ID: mdl-31862670

ABSTRACT

BACKGROUND: Quantitative gait analysis produces a vast amount of data, which can be difficult to analyze. Automated gait classification based on machine learning techniques bear the potential to support clinicians in comprehending these complex data. Even though these techniques are already frequently used in the scientific community, there is no clear consensus on how the data need to be preprocessed and arranged to assure optimal classification accuracy outcomes. RESEARCH QUESTION: Is there an optimal data aggregation and preprocessing workflow to optimize classification accuracy outcomes? METHODS: Based on our previous work on automated classification of ground reaction force (GRF) data, a sequential setup was followed: firstly, several aggregation methods - early fusion and late fusion - were compared, and secondly, based on the best aggregation method identified, the expressiveness of different combinations of signal representations was investigated. The employed dataset included data from 910 subjects, with four gait disorder classes and one healthy control group. The machine learning pipeline comprised principle component analysis (PCA), z-standardization and a support vector machine (SVM). RESULTS: The late fusion aggregation, i.e., utilizing majority voting on the classifier's predictions, performed best. In addition, the use of derived signal representations (relative changes and signal differences) seems to be advantageous as well. SIGNIFICANCE: Our results indicate that great caution is needed when data preprocessing and aggregation methods are selected, as these can have an impact on classification accuracies. These results shall serve future studies as a guideline for the choice of data aggregation and preprocessing techniques to be employed.


Subject(s)
Gait Analysis/methods , Gait Disorders, Neurologic/diagnosis , Gait/physiology , Support Vector Machine , Gait Disorders, Neurologic/physiopathology , Humans , Principal Component Analysis , Young Adult
2.
IEEE J Biomed Health Inform ; 22(5): 1653-1661, 2018 09.
Article in English | MEDLINE | ID: mdl-29990052

ABSTRACT

This paper proposes a comprehensive investigation of the automatic classification of functional gait disorders (GDs) based solely on ground reaction force (GRF) measurements. The aim of this study is twofold: first, to investigate the suitability of the state-of-the-art GRF parameterization techniques (representations) for the discrimination of functional GDs; and second, to provide a first performance baseline for the automated classification of functional GDs for a large-scale dataset. The utilized database comprises GRF measurements from 279 patients with GDs and data from 161 healthy controls (N). Patients were manually classified into four classes with different functional impairments associated with the "hip", "knee", "ankle", and "calcaneus". Different parameterizations are investigated: GRF parameters, global principal component analysis (PCA) based representations, and a combined representation applying PCA on GRF parameters. The discriminative power of each parameterization for different classes is investigated by linear discriminant analysis. Based on this analysis, two classification experiments are pursued: distinction between healthy and impaired gait (N versus GD) and multiclass classification between healthy gait and all four GD classes. Experiments show promising results and reveal among others that several factors, such as imbalanced class cardinalities and varying numbers of measurement sessions per patient, have a strong impact on the classification accuracy and therefore need to be taken into account. The results represent a promising first step toward the automated classification of GDs and a first performance baseline for future developments in this direction.


Subject(s)
Gait Disorders, Neurologic/diagnosis , Gait Disorders, Neurologic/physiopathology , Signal Processing, Computer-Assisted , Adult , Case-Control Studies , Databases, Factual , Foot/physiology , Gait/physiology , Humans , Machine Learning , Middle Aged , Principal Component Analysis , Young Adult
3.
Stud Health Technol Inform ; 144: 163-6, 2009.
Article in English | MEDLINE | ID: mdl-19592756

ABSTRACT

Reviews and few non-controlled studies showed the effectiveness of several specific designed computer video-games as an additional form of treatment in several areas. However, there is a lack in the literature of specially designed serious-games for treating mental disorders. Playmancer (ICT European initiative) aims to develop and assess a serious videogame that may help to treat underlying processes (e.g. lack of self-control strategies) in Eating and Impulse control disorders. Preliminary data will be shown.


Subject(s)
Disruptive, Impulse Control, and Conduct Disorders , Video Games , Humans
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