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J Comb Chem ; 10(1): 142-7, 2008.
Article in English | MEDLINE | ID: mdl-18062673

ABSTRACT

A diverse collection of pyrroles has been prepared using a one-pot, domino aldehyde/amine condensation, [3,3]-aza-Claisen rearrangement, imine-allene cyclization strategy. This protocol was accelerated by microwave irradiation and provided very good levels of conversion after reacting for only 30 min.


Subject(s)
Alkadienes/chemistry , Aza Compounds/chemistry , Combinatorial Chemistry Techniques/methods , Imines/chemistry , Microwaves , Pyrroles/chemical synthesis , Cyclization , Molecular Structure , Pyrroles/chemistry
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