Subject(s)
Pancuronium/therapeutic use , Respiration, Artificial , Strychnine/poisoning , Humans , Male , Middle AgedSubject(s)
Alcoholic Intoxication/therapy , Renal Dialysis , Adult , Alcoholic Intoxication/blood , Female , Humans , Suicide, AttemptedSubject(s)
Epiglottitis/complications , Laryngitis/complications , Respiratory Insufficiency/etiology , Streptococcal Infections/complications , Acute Disease , Adult , Chloramphenicol/therapeutic use , Epiglottitis/drug therapy , Humans , Male , Ornidazole/therapeutic use , Streptococcal Infections/drug therapy , Streptococcus pyogenes , Ticarcillin/therapeutic useABSTRACT
In this cooperative trial, 181 patients with various urinary tract infections were treated by dibekacin, a new hemi-synthetic aminoglycoside. Clinical and bacteriological results confirm the efficacy of dibekacin in this indication. Local and systemic tolerance, and thus renal and cochleo-vestibular, were very satisfactory.
Subject(s)
Dibekacin/therapeutic use , Kanamycin/analogs & derivatives , Urinary Tract Infections/drug therapy , Dibekacin/adverse effects , HumansABSTRACT
During an open multicentric trial (17 centers), we have treated 62 septicemia by dibekacin, alone or associated with other antibacterial drugs. Taking into account the degree of severity of these patients, the results are considered satisfactory in 47 patients. 15 failures were noted (including 9 deaths). General and local tolerance were good, in spite of the duration of treatment.
Subject(s)
Dibekacin/therapeutic use , Kanamycin/analogs & derivatives , Sepsis/drug therapy , Adult , Aged , Anti-Bacterial Agents/therapeutic use , Dibekacin/adverse effects , Drug Therapy, Combination , Female , Humans , Male , Middle AgedABSTRACT
Major abdominal surgery often involves severe postoperative infections with various pathogens: enterobacteriaceae, staphylococcus and anaerobic bacteria. For this reason a strong antibiotherapy can be necessary in the case of an infectious disease. Dibekacin was administered at a daily dose of 3 mg/kg to 22 patients suffering from very severe postoperative infection. In all the cases dibekacin was combined with a beta-lactamine and in some with nitro-imidazole derivative. The results were especially favourable in all of these cases and a good tolerance was observed.