ABSTRACT
It is possible to inject highly supersaturated aqueous solutions of gas through a small capillary into an aqueous environment without the formation of significant gas bubbles. Such a technique has considerable potential therapeutic value in the treatment, for example, of heart attacks and strokes. The present paper is the second in a series (see Brereton et al. [1]) investigating the basic phenomenon behind this surprising effect. Recent experiments clearly demonstrate that the nucleation, when it does occur, results from heterogeneous nucleation on the interior surface of the distal end of the capillary. This paper describes the effects of the treatment of this interior surface on the nucleation processes and the results of high speed video observations of the phenomena. A heterogeneous nucleation model is presented which is in accord with the experimental observations.
Subject(s)
Gases/administration & dosage , Gases/chemistry , Injections/instrumentation , Oxygen/administration & dosage , Oxygen/chemistry , Rheology/instrumentation , Solutions/chemistry , Benzophenones , Capillary Action , Carbon Dioxide , Equipment Design , Injections/methods , Ketones/chemistry , Microspheres , Oxygen/blood , Polyethylene Glycols/chemistry , Polymers , Pressure , Rheology/methods , Sensitivity and Specificity , Silicon Dioxide/chemistry , Surface Properties , Video Recording , Water/chemistryABSTRACT
This paper presents a spectral analysis of the response of a fluid containing bubbles to the motions of a wall oscillating normal to itself. First, a Fourier analysis of the Rayleigh-Plesset equation is used to obtain an approximate solution for the nonlinear effects in the oscillation of a single bubble in an infinite fluid. This is used in the approximate solution of the oscillating wall problem, and the resulting expressions are evaluated numerically in order to examine the nonlinear effects. Harmonic generation results from the nonlinearity. It is observed that the bubble natural frequency remains the dominant natural frequency in the volume oscillations of the bubbles near the wall. On the other hand, the pressure perturbations near the wall are dominated by the first and second harmonics present at twice the natural frequency while the pressure perturbation at the natural frequency of the bubble is inhibited. The response at the forcing frequency and its harmonics is explored along with the variation with amplitude of wall oscillation, void fraction, and viscous and surface tension effects. Splitting and cancellation of frequencies of maximum and minimum response due to enhanced nonlinear effects are also observed.
