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1.
BMJ Case Rep ; 20152015 Jan 20.
Article in English | MEDLINE | ID: mdl-25604502

ABSTRACT

Kikuchi-Fujimoto disease (KFD) is an unusual cause of lymphadenopathy and fever. Pregnancy associated with KFD presents as a diagnostic dilemma for clinicians. The diagnosis can be confirmed with invasive biopsies or non-invasive gene analysis. We report a case of a 24-year-old woman at 18 weeks' gestation with a neck lump and histologically confirmed KFD.


Subject(s)
Acetaminophen/administration & dosage , Analgesics, Non-Narcotic/administration & dosage , Anti-Bacterial Agents/administration & dosage , Fever/pathology , Histiocytic Necrotizing Lymphadenitis/diagnosis , Lymph Nodes/pathology , Penicillins/administration & dosage , Adult , Biopsy, Fine-Needle , Diagnosis, Differential , Female , Fever/etiology , Gestational Age , Histiocytic Necrotizing Lymphadenitis/drug therapy , Histiocytic Necrotizing Lymphadenitis/pathology , Humans , Pregnancy , Pregnancy Complications , Pregnancy Outcome
2.
J Vasc Surg ; 44(6): 1279-84; discussion 1284, 2006 Dec.
Article in English | MEDLINE | ID: mdl-17145430

ABSTRACT

OBJECTIVE: Varicose vein recurrence after surgery occurs in up to 60% of patients. A variety of technical factors have been implicated, but biological factors such as neovascularization have more recently been proposed. The objective of this study was to characterize the relative contribution of technical and biological factors to recurrence in a large prospective series of recurrent varicose veins. METHODS: Duplex and operative findings were recorded prospectively in a consecutive series of 500 limbs undergoing surgery for recurrent varicose veins between 1995 and 2005 in a university teaching hospital. Only limbs with previous saphenofemoral junction surgery were included. All limbs had preoperative duplex mapping by an accredited vascular technician who assessed the status of the great saphenous vein (GSV) in the thigh and groin, sought sonographic evidence of neovascularization, and reported on the presence of reflux in the short saphenous vein and perforator sites (typical and atypical). All operations were performed with an attending vascular surgeon as the lead operator. RESULTS: Primary GSV surgery was incomplete in 83.2% of limbs. A completely intact GSV system was present in 17.4% of limbs. An incompetent thigh saphenous vein was present in 44.2% of limbs, 37.6% had GSV stump incompetence with one or more intact tributaries, and 16% had both a residual thigh GSV and an incompetent stump with intact tributaries. Non-GSV sites of reflux were identified in 25% of limbs. Neovascularization was identified on duplex scanning in 41 (8.2%) limbs. However, in 27 of these, surgical exploration revealed a residual GSV stump with 1 or more significant tributaries. Each of the remaining 14 (2.8%) limbs had a residual incompetent thigh GSV. CONCLUSIONS: Despite reports to the contrary, neovascularization occurs in a relatively small proportion of patients with recurrent varicose veins. All recurrent varicose veins associated with duplex-diagnosed neovascularization are also associated with persistent reflux in the GSV stump tributaries, thigh GSV, or both. Recurrence after primary varicose vein surgery is associated with inadequate primary surgery or progression of disease, and neovascularization alone is not a cause of recurrent varicose veins.


Subject(s)
Neovascularization, Pathologic/etiology , Saphenous Vein/diagnostic imaging , Varicose Veins/complications , Venous Insufficiency/complications , Female , Humans , Male , Middle Aged , Neovascularization, Pathologic/diagnostic imaging , Prospective Studies , Recurrence , Reoperation , Saphenous Vein/surgery , Treatment Outcome , Ultrasonography, Doppler, Duplex , Varicose Veins/diagnostic imaging , Varicose Veins/prevention & control , Varicose Veins/surgery , Vascular Surgical Procedures , Venous Insufficiency/diagnostic imaging , Venous Insufficiency/prevention & control , Venous Insufficiency/surgery
3.
Paediatr Anaesth ; 14(12): 1016-20, 2004 Dec.
Article in English | MEDLINE | ID: mdl-15601352

ABSTRACT

A 2 year-old boy presented with acute upper airway obstruction following a 15-month history of noisy breathing and hoarseness. An urgent laryngotracheal bronchoscopy was performed following inhalational induction of anesthesia. Using a fiberoptic bronchoscope, visualization of the larynx through a laryngeal mask airway revealed a flat plastic Christmas tree embedded within granulomatous cords causing almost complete obstruction and requiring tracheostomy prior to extraction. Twelve days later, the tracheostomy was successfully decannulated with the child's voice beginning to normalize. The family remembered the decoration from Christmas celebrations 2 years prior and recalled a coughing episode that predated the onset of hoarseness.


Subject(s)
Airway Obstruction/diagnosis , Airway Obstruction/surgery , Foreign Bodies/surgery , Larynx/diagnostic imaging , Airway Obstruction/etiology , Anesthesia, Inhalation/methods , Anesthetics, Inhalation , Bronchoscopy/methods , Child, Preschool , Diagnosis, Differential , Fiber Optic Technology/methods , Foreign Bodies/diagnosis , Hoarseness/etiology , Humans , Laryngeal Masks , Male , Methyl Ethers , Radiography , Respiratory Sounds/etiology , Sevoflurane , Tracheostomy/methods
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