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Immunohistological study of captopril-induced late cutaneous eruptions.

Bretin, N; Dreno, B; Bureau, B; Litoux, P.

Dermatologica ; 177(1): 11-5, 1988.

Article in English | MEDLINE | ID: mdl-2460382

ABSTRACT

Immunohistological study of dermal infiltrate from two pemphigus- and one captopril-induced lichenoid eruption showed the presence of a CD8 (T suppressor) infiltrate that resembled that found in skin eruptions induced by graft-versus-host disease. It is suggested that a T cell cytotoxic reaction occurs in the epidermis that might be triggered by captopril-induced modification of keratinocytic antigens.

Subject(s)

Captopril/adverse effects , Drug Eruptions/etiology , Lichen Planus/chemically induced , Pemphigus/chemically induced , Aged , Aged, 80 and over , Drug Eruptions/metabolism , Epidermis/metabolism , Epidermis/pathology , Female , Fluorescent Antibody Technique , HLA-DR Antigens/analysis , Humans , Keratins/metabolism , Lichen Planus/metabolism , Male , Pemphigus/metabolism , T-Lymphocytes, Regulatory/metabolism , Time Factors

[On temporal arteritis (Horton's disease); notes on a case]. / Contributii la studiul arteritei temporale (boala Horton); în legatura cu un caz.

Bretin, N; Pecurariu, O; Puscariu, H.

Med Interna (Bucur) ; 23(5): 633-6, 1971 May.

Article in Romanian | MEDLINE | ID: mdl-5567988

Subject(s)

Giant Cell Arteritis/diagnosis , Aged , Blindness/etiology , Brachial Plexus Neuritis/etiology , Female , Fever/etiology , Giant Cell Arteritis/complications , Humans

[On the medical treatment of spondyloses (study of 396 patients)]. / Consideratii asupra tratamentului medical al spondilozelor (studiu efectuat pe 396 de bolnavi)

Aurel, I; Dumitrescu, D; Bretin, N; Dogaru, M.

Med Interna (Bucur) ; 23(2): 143-8, 1971 Feb.

Article in Romanian | MEDLINE | ID: mdl-5549615

Subject(s)

Spinal Diseases/drug therapy , Adrenal Cortex Hormones/therapeutic use , Anabolic Agents/therapeutic use , Analgesics/therapeutic use , Anti-Inflammatory Agents/therapeutic use , Female , Humans , Male , Neuromuscular Depolarizing Agents/therapeutic use , Physical Therapy Modalities , Pyridoxine/therapeutic use , Spinal Diseases/radiotherapy , Thiamine/therapeutic use

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