ABSTRACT
Leishmania species are obligate intracellular parasites transmitted by various types of female sand flies. The clinical syndrome that results depends on a number of factors including the Leishmania species and immune response of the host. Here, we report successful treatment of lingual leishmaniasis complicating visceral disease in an immunocompetent patient.
Subject(s)
Leishmaniasis, Visceral/drug therapy , Leishmaniasis/drug therapy , Tongue Diseases/drug therapy , Amphotericin B/therapeutic use , Animals , Antiprotozoal Agents/therapeutic use , Biopsy , Humans , Immunocompetence , Insect Vectors/parasitology , Leishmaniasis/complications , Leishmaniasis/parasitology , Leishmaniasis/pathology , Leishmaniasis, Visceral/complications , Leishmaniasis, Visceral/parasitology , Leishmaniasis, Visceral/pathology , Male , Middle Aged , Psychodidae/parasitology , Tongue Diseases/parasitology , Tongue Diseases/pathologyABSTRACT
Cavitary pneumonia caused by Rhodococcus equi may occur in patients with defective cell-mediated immunity. Prolonged CD4 lymphopenia may develop in patients with chronic lymphocytic leukemia who receive fludarabine. The authors report the first case of a patient with chronic lymphocytic leukemia who developed R equi pneumonia after fludarabine therapy.
Subject(s)
Actinomycetales Infections/microbiology , Leukemia, Lymphoid/drug therapy , Lymphopenia/drug therapy , Pneumonia, Bacterial/microbiology , Rhodococcus equi/isolation & purification , Actinomycetales Infections/drug therapy , Aged, 80 and over , Anti-Bacterial Agents/therapeutic use , Antineoplastic Agents/therapeutic use , Bronchoalveolar Lavage Fluid/microbiology , CD4 Lymphocyte Count , Chronic Disease , Female , Humans , Opportunistic Infections/microbiology , Pneumonia, Bacterial/drug therapy , Vidarabine/analogs & derivatives , Vidarabine/therapeutic useABSTRACT
Infections due to nontyphoidal salmonellae are common, and their incidence has been increasing in the last few years. In this case report, we document the unusual finding of a gluteal abscess caused by Salmonella typhimurium in the absence of detectable bacteremia. Fluoroquinolones remain an important treatment option for salmonellosis, and to avoid potential treatment failures, we underscore the importance of routine screening for nalidixic acid susceptibility with all extraintestinal Salmonella isolates. To our knowledge, this is the first published case of S typhimurium gluteal abscess in the absence of bacteremia and risk factors for salmonellosis.
