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Med Image Comput Comput Assist Interv ; 16(Pt 3): 307-14, 2013.
Article in English | MEDLINE | ID: mdl-24505775

ABSTRACT

Genital prolapse is a pathologic hyper-mobility of the organs that forms the pelvic system. Although this is common condition, the pathophysiology of this disorder is not well known. In order to improve the understanding of its origins, we recreate--virtually--this biomechanical pathology using numerical simulation. The approach builds on a finite element model with parameters measured on several fresh cadavers. The meshes are created from a MRI of a healthy woman and the simulation includes the mechanical interactions between organs (contacts, ligaments, adhesion...). The model is validated through comparison of functional mobilities of the pelvic system observed on a dynamic MRI. We then propose to modify, step by step, the model and its parameters to produce a pathologic situation and have a better understanding of the process. It is not a formal proof but the numerical experiments reinforce the clinical hypothesis on the multifactorial origins of the pathology.


Subject(s)
Magnetic Resonance Imaging/methods , Models, Biological , Pelvic Organ Prolapse/pathology , Pelvic Organ Prolapse/physiopathology , Pelvis/pathology , Pelvis/physiopathology , Aged , Cadaver , Computer Simulation , Elastic Modulus , Female , Humans , Models, Anatomic , Stress, Mechanical , Tensile Strength
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