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HLA antigen associations in hypertrophic cardiomyopathy.

Mourant, A J; Kafetz, K M; Brigden, W W; Awad, J; D'Amaro, J; Yeatman, N W; Festenstein, H.

Tissue Antigens ; 20(5): 389-93, 1982 Nov.

Article in English | MEDLINE | ID: mdl-6818713

ABSTRACT

Histocompatibility antigen testing has been carried out in 20 unrelated normotensive English Caucasoids with hypertrophic cardiomyopathy and in 17 relatives, six of whom also had the disease. A strong association with the HLA-DRw6 antigen complex was found (P = 0.0036) but it was no longer significant after correction for the 52 antigens tested (P = 0.1701).

Subject(s)

Cardiomyopathy, Hypertrophic/immunology , HLA Antigens/genetics , Adolescent , Adult , Aged , Cardiomyopathy, Hypertrophic/epidemiology , Cardiomyopathy, Hypertrophic/genetics , Female , Genes, MHC Class II , HLA Antigens/immunology , HLA-C Antigens , HLA-DR Antigens , Histocompatibility Antigens Class II/immunology , Humans , London , Male , Middle Aged

ABSTRACT

Subject(s)

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